Tumori Laringiene

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TUMORI BENIGNE 1.POLIPUL LARINGIAN AP: hiperplazie conjunctivoepiteliala cu ax central vascular in zona de turbionaj vascular al CV Clinic: SUB=disfonie,diplofonie OB=formatiune pediculata sau sesila,coloratie rosie sau violacee in 1/3 ant a CV Tratament:extirpare in laringoscopie suspendata+AP la zona de contact cu mucoasa normala PAILOMATOZA LARINGIANA AP:metaplazie epiteliala Clinic: SUB Co=disfonie+insuficienta respiratorie Ad=disfonie OB=formatiuni conopidiforme de coloratie alb-roz Co=multiple Ad=unica Evolutie: Co=recidiva;Ad=trasformare maligna Tratament:extirpare prin larigoscopie suspendata+AP obligator la Ad CANCERUL DE LARINGE Etiologie 25-35% din CADS barbat=femei factori favorizanti -tutun alcool - fct profesionali=azbest,produsi petrolieri stari precanceroase -laringite cr rosii, albe -papilomul ANATOMIE Bariere anatomice I extralaringiene –tiroid - metaplazie osoasa la niv. com ant. -cricoid -membr.hioepiglotica limiteaza extensia spre baza limbii si lojaTHE II intralaringiene –membr.cricovocala -membr.patrulatera Puncte slabe I extensie extralaringiana a) com ant –absenta pericondru - metaplazie osoasa -insertia lig. tiroepiglotic b) membr.cricotiroidiana II extensie intralaringiana –epiglota cu orificii -prelungire diverticulara a ventriculului -spatiu paraglotic

Clinic=diagnostic + SUB- disfonie peste 15 zile - disfagie - dispnee -adenopatie 25-50% OB tumora vegetanta;infiltrativa:ulcerovegetanta -a 2-a localizare Rgrf –laringe profil tomografie pulmonara TNM T1=limitata T2=extensie cu mobilitate normala T3=extensie fara mobilitate T4=extensie regiuni vecine Tratament complex =chimio+chir.(tumora primara +ariile ggl.)+cobaltoterapie+imunologic Supravietuire (5ani) T1=80-95% T2=70-80% T3=36-57% T4=10%

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