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Host (Penjamu) -Host: Manusia. Semua umur dapat tertular TB paru. -Kelompok resiko tertinggi: Kelompok usia produktif, penderita HIV, perilaku merokok, dan penderita penyakit yang merusak kekebalan tubuh
Agent
Environment
Agent: Mycobacterium tuberculosis
Kondisi lingkungan rumah seperti ada tidaknya sinar ultraviolet, ventilasi yang buruk, kelembaban, suhur rumah, dan kepadatan penghuni rumah.