Jurnal Bahasa Inggris.docx

Generic name Bronchodilators b-agonists Non-selective Isoprenaline

Partially selective Orciprenaline Selective short-acting Fenoterol Pirbuterol Reproterol Rimiterol Salbutamol Terbutaline Tulobuterol Selective long- acting Salmeterol Bambuterol

Interacting drugs

Potential effect

Adrenergic neurone reserpine, bretylium

Measures to take

blockers, Increased sensitivity to directly acting sympathomimetic amines may cause hypertension Tricyclic antidepressants Potentiation of sympathomimetic effects due to inhibition of neuronal uptake b-blockers Antagonism of bronchodilator effect of sympathomimetics. Also risk of hypertension Diethylpropion, mazindol, Pressor effects may be phentermine potentiated Theophylline Decreased plasma levels of theophylline, increased risk of hypokalaemia Monoamine oxidase inhibitors Possible interaction (MAOls) b-blockers Mutual antagonism

Avoid concurrent use

b-blockers

Mutual antagonism

Avoid concurrent use

Theophylline, corticosteroids

Increased risk of hypokalaemia

Monitor serum potassium levels in patients with severe asthma

b-blockers b-blockers suxamethonium

Mutual antagonism Mutual antagonism Prolonged paralysis

Avoid concurrent use

Avoid concurrent use

Avoid concurrent use Use with caution

Use with caution Avoid concurrent use

Avoid concurrent use

Xanthines Aminophylline Choline theophyllinate Lysine theophyllinate

Cimetidine, viloxazine, ciprofloxacin, erythromycin, isoniazid, oral contraceptives, mexiletine, interferons, thiabendazole, propranolol, diltiazem, verapamil, allopurinol, disulfiram, hydrocortisone, fluconazole, troleandomycin, BCG vaccine, vidarabine, enoxacin, fluvoxamine, diuretics Lithium

Increased plasma xanthine may Occur

levels

of Monitor plasma xanthine levels reduce dose if necessary

Increased excretion of lithium Monitor lithium levels reducing plasma levels