Daftar Isi.docx

DAFTAR SINGKATAN

AAP

: Academy of Pediatrics

ACOG

: American College of Obstetrics and Gynaecology

AGA

: Appropriate for Gestational Age

BBLR

: Berat Badan Lahir Rendah

BBLER

: Berat Bayi Lahir Ekstrem Rendah

BBLSR

: Berat Bayi Lahir Sangat Rendah

BMI

: Body Mass Index

ELBW

: Extremely Low Birth Weight

IDAI

: Ikatan Dokter Anak Indonesia

IMT

: Indeks Massa Tubuh

IUGR

: Intrauterine Growth Restriction

LBW

: Low Birth Weight

LGA

: Large for Gestational Age

NICU

: Neonatal Intensive Care Unit

NIH

: National Institute of Health

NO

: Nitrit Oksida

NTD

: Neural Tube Defect

PJT

: Pertumbuhan Janin Terhambat

RBP4

: Retinol Binding Protein 4

ROS

: Reactive Oxygen Species

SGA

: Small for Gestational Age

SSP

: Sistem Saraf Pusat

VLBW

: Very Low Birth Weight

WHO

: World Health Organization

iii

DAFTAR ISI HALAMAN JUDUL...................................................................................... i LEMBAR PERSETUJUAN........................................................................... ii DAFTAR SINGKATAN ............................................................................... iii DAFTAR ISI .................................................................................................. iv DAFTAR TABEL .......................................................................................... vi DAFTAR LAMPIRAN .................................................................................. vii

BAB I. PENDAHULUAN 1.1 Latar Belakang ................................................................................ 1 1.2 Rumusan Masalah ........................................................................... 3 1.3 Tujuan Penelitian ............................................................................ 3 1.4 Hipotesis ......................................................................................... 4 1.5 Manfaat Penelitian .......................................................................... 4 BAB II. TINJAUAN PUSTAKA 2.1 Luaran Neonatal.............................................................................. 5 2.1.1 Asfiksia Neonatorum ............................................................ 8 2.1.2 Berat Badan Lahir Rendah.................................................... 12 2.1.3 Makrosomia .......................................................................... 13 2.1.4 Hipoglikemia ........................................................................ 14 2.1.5 Kelainan Kongenital ............................................................. 15 2.1.6 Stillbirth ................................................................................ 17 2.2 Obesitas........................................................................................... 18 2.2.1 Indeks Massa Tubuh ............................................................. 18 2.2.3 Definisi Obesitas .................................................................. 19 2.2.3 Kategori Obesitas ................................................................. 19 2.2.4 Faktor yang Mempengaruhi Obesitas ................................... 20 2.3 Hubungan antara Obesitas pada Kehamilan dan Luaran Neonatal 21 2.4 Kerangka Teori ............................................................................... 27 2.5 Kerangka Konsep............................................................................ 28 BAB III METODE PENELITIAN 3.1 Metode Penelitian ........................................................................... 29 3.1.1 Jenis Penelitian ...................................................................... 29 3.1.2 Waktu dan Tempat Penelitian ................................................ 29 3.2 Populasi dan Sampel ....................................................................... 29 3.2.1 Populasi Penelitian ............................................................... 29 3.2.2 Sampel Penelitian ................................................................. 29 3.2.3 Cara Pengambilan Sampel .................................................... 30 3.2.4 Kriteria Inklusi dan Ekslusi .................................................. 30 3.2.4.1 Kriteria Inklusi ......................................................... 30 3.2.4.2 Kriteria Eksklusi ...................................................... 30 iv

3.3 Variabel Penelitian.......................................................................... 31 3.3.1 Variabel Terikat ..................................................................... 31 3.3.2 Variabel Bebas ....................................................................... 31 3.4 Definisi Operasional ....................................................................... 31 3.5 Cara Pengumpulan Data ................................................................. 32 3.6 Cara Pengolahan dan Analisis Data ................................................ 32 3.6.1. Cara Pengolahan Data ........................................................... 32 3.6.2. Analisis Data ......................................................................... 32 3.7 Kerangka Operasional .................................................................... 39 3.8 Rencana Kegiatan ........................................................................... 40 3.9 Anggaran......................................................................................... 40 BAB IV JUSTIFIKASI ETIK 4.1 Rangkuman Karakteristik Penelitian .............................................. 41 4.2 Analisis Kelayakan Etik ................................................................. 41 4.3 Prosedur Informed Consent ............................................................ 41 4.4 Kesimpulan ..................................................................................... 42 DAFTAR PUSTAKA ................................................................................... 43 LAMPIRAN .................................................................................................. 50 BIODATA ..................................................................................................... 51

v

DAFTAR TABEL Tabel Halaman 1. Sistem Skor APGAR ................................................................................. 6 2. Klasifikasi IMT berdasarkan WHO ........................................................... 19 3. Dummy Table Distribusi Pasien yang Bersalin di RSUP Dr. Mohammad Hoesin Palembang menurut Indeks Massa Tubuh..................................... 33 4. Dummy Table Distribusi Pasien yang Bersalin di RSUP Dr. Mohammad Hoesin Palembang menurut Luaran Neonatal ........................................... 33 5. Dummy Table Hubungan antara Obesitas pada Kehamilan dan Kejadian BBLR ......................................................................................................... 34 6. Dummy Table Hubungan antara Obesitas pada Kehamilan dan Kejadian Asfiksia Neonatorum ................................................................................. 34 7. Dummy Table Hubungan antara Obesitas pada Kehamilan dan Kejadian Makrosomia ............................................................................................... 35 8. Dummy Table Hubungan antara Obesitas pada Kehamilan dan Kejadian Hipoglikemia ............................................................................................. 35 9. Dummy Table Hubungan antara Obesitas pada Kehamilan dan Kelainan Kongenital.................................................................................................. 36 10. Dummy Table Hubungan antara Obesitas pada Kehamilan dan Kejadian Stillbirth ..................................................................................................... 36 11. Dummy Table Analisis Tingkatan Obesitas terhadap Kejadian Asfiksia Neonatorum ............................................................................................... 37 12. Dummy Table Analisis Tingkatan Obesitas terhadap Kejadian BBLR ..... 37 13. Dummy Table Analisis Tingkatan Obesitas terhadap Kejadian Makroso mia ............................................................................................................. 37 14. Dummy Table Analisis Tingkatan Obesitas terhadap Kejadian Hipoglike mia ............................................................................................................. 38 15. Dummy Table Analisis Tingkatan Obesitas terhadap Kelainan Kongenit al ................................................................................................................ 38 16. Dummy Table Analisis Tingkatan Obesitas terhadap Kejadian Stillbirth . 38

vi

DAFTAR LAMPIRAN Lampiran 1.

Halaman

Lembar Konsultasi ..................................................................................50

vii