Ceftriaxone Rocephin

INDEX Generic Name ceftriaxone

Trade Name Rocephin

Peak Onset end of infusion rapid Why is your patient taking this medication?

NURS 2236 Clinical Form 3: Clinical Medications Worksheet (You will need to made additional copies of these forms) Classification Dose Route Time/Frequency anti-infectives

Duration 12-24 hr

Mechanism of action and indications Treatment of skin and skin structure infections. Bone and joint infections. Complicated and uncomplicated UTIs Uncomplicated gynecological infections including gonorrhea. Lower RTIs; intra-abdominal infections; Septicemia; Meningitis; Otitis media; Perioperative prophylaxis. Bactericidal action against susceptible bacteria. Not active against MRSA or enterococci. Interactions with other patient drugs, OTC, or herbal medicines (ask patient specifically) Probenecid

1-2g

IV

every 12-24 hr

For IV meds, compatability with IV drips and/or solutions

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitiviy to cephalosporins. Serious hypersensitivity to penicillins; combined severe hepatic and renal impairment; history of GI disease, especially colitis; prenancy and lactation

Common side effects Seizures (high doses); pseudomembranous colitis; diarrhea; cholelthiasis; sludging in the gallbladder; rashes; urticaria; bleeding; eosinophilia; hemolytic anemia; leudopenia; thrombocytosis; phlebitis at IV site; allergic reactions including anaphylaxis, superinfection. Lab value alterations caused by medicine

Be sure to teach the patient the following about this medication Report signs of superinfection (furry overgrowth on the tongue, vaginal itching or discharge, loose or foul-smelling stools) and allergy. If ever and diarrhea develop call doctor, especially if stool contains blood, pus, or mucus. Do not treat the diarrhea. Nursing Process - Assessment (Pre-administration assessment Assess patient for infection Vital signs; appearance of wound, sputum,urine, and stool; WBC and beginning of and throughout therapy. Allergy to medication

Assessment Why would you hold or not give this med? allergy anaphylaxis

Evaluation Check after giving Resolution of the signs and symptoms of infections. Length of time for complete resolution depends on the organism and the site of infection. Decreased incidence of infection when used for prophylaxis.