Theory Paper.docx

SRI VENKATESWARA VETERINARY UNIVERSITY COLLEGE OF VETERINARY SCIENCE, TIRUPATI DEPARTMENT OF PHARMACOLOGY & TOXICOLOGY VPT-411, CHEMOTHERAPY (2+0) INTERNAL THEORY EXAMINATION PART- B I.D No.__________________ Date: 01-04-2014

Max Marks: 40 M Time: 75 min

Answer any FOUR questions. Write all parts of a question at one place

1.

Define chemotherapy. Classify antimicrobial agents on basis of their mechanism of action, spectrum of activity and sources. Write the principles of chemotherapy.

2.

10 M

Classify tetracycline and write about their mechanism of action, clinical uses and adverse effects 10 M

3.

Classify Antiviral drugs and explain in detail the mechanism of action, antiviral spectrum & clinical uses of Acyclovir

10 M

4.

a. Classify Antifungal agents. Write the mechanism of action of Polyene antibiotics with clinical uses 5×2=10 M b. What are β-lactum antibiotics. Explain their mechanism of action.

5.

a. Describe mechanism of sulphonamides along with their side effects

5×2=10M

b. Describe briefly about anti microbial drug resistance

6.

Answer any FOUR of the following a. Urinary antiseptics b. Avermectins c.

Mechanism of action of Fluroquinolones

d.

Insect growth regulators

e.

Adverse effect of aminoglycosides

f.

Potentiated Sulphonamides

2.5×4= 10 M