Teguh T_abcd Reaksi Transfusi_2018.pdf

Teguh Triyono Faculty of Medicine Universitas Gadjah Mada/ Sardjito Hospital Yogyakarta 1

Recruit Pre-transfusion testing

Screen Donor

Infectious Disease Test

Issue

Medical Decission to transfuse

Collect & Prepare

Product Process

Monitor & Evaluate Administer (Bedside)

Recruit Pre-transfusion testing

Screen Donor

Infectious Disease Test

Issue

Medical Decission to transfuse

Collect & Prepare

Blood Safety Transfusion Safety

Monitor & Evaluate Administer (Bedside)

An adverse transfusion reaction is “an undesirable response or effect” in a patient temporarily associated with the administration of blood or blood component.

NHSN manual: biovigilance component protocol hemovigilance module, June 2011. Guidelines and procedures for monitoring hemovigilance. http://www.cdc.gov/nhsn/bio.html.

Transfusion Reactions and Incidents ?

The risks of blood transfusion :

• • • • • •

Immune / serologic reaction Blood transmitted infections TRALI TACO GvHD Mistransfusion

REPORTED TRANSFUSION REACTIONS 28 8%

6 3 2% 1%

3 1%

63 19%

Febrile 55 16%

Chill Urtika Dispnoe Palpitation Hypotension

181 53%

Others

Reaksi Transfusi vs Komponen Darah

Reaksi Transfusi

Komponen darah

Komponen Darah Untuk Transfusi Red Blood Cells Platelets Fresh Frozen Plasma (FFP) Cryoprecipitated Anti-hemophilic Factor Granulocytes

A

Apa jenis reaksinya ?

D

Database

B

• Berlakukan SOP • Pasien & Komponen darah

C

Cari faktor kausa

11

ALERTING SYSTEM

12

http://haemovigilanceindo.com • National •

haemovigilance system is not yet formally held in Indonesia, There is a start of website available.

Simpulan • Reaksi transfusi dapat terjadi oleh karena faktor pasien maupun komponen darah. • Konsep A-B-C-D dapat menjadi salah satu pedoman dalam tahapan mitigasi reaksi transfusi.

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