Renin-angiotensin System
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Renin-Angiotensin System Liver
Beta Blockers
Angiotensinogen Kininogens Plasma Kallikrein BKB 2 Receptor
Renin
Substance P
neutral endopeptidase
Chymase
prolylendeptidase
Endothelin I ACE Angiotensin Converting Enzyme
Inactive Peptides
Angiotensin (1-7) Receptor 3 AT 3
Angiotensin I
Big endothelin Bradykinin
Vasodilation , release of nitric oxide, prostacyclin, and endothelium derived hyperpolarizing factor, inhibition of platelet adhesion, and inhibition of smooth muscle proliferation.
Kidney
ACE Inhibitors
Capillary
Vasodilation & potentiate bradykinin
Inhibition of
Adrenal Cortex Aldosterone Metabolsim
Angiotensin II
Angiotensin II Receptor 1 AT 1
Angiotensin II Receptor Aldosterone Secretion Angiotensin II Receptor Blockers
Systemic Vasoconstricition & expression of Plasminogen Activator Inhibitor-1 Angiotensin III Arginylaminopeptidase Glutamylaminopeptidase Angiotensin IV Angiotensin IV(3-8) Receptor 4 AT 4
Learning and memory
Posterior pituitary Vasopressin release Angiotensin II Receptor 2 AT 2
Sodium resorption from the kidney distal kubules Lumen Sodium Channel
Na +
Vasodialation & Apoptosis
Sodium Channel Modulators
Aldosterone Receptor
Beta Blockers
Angiotensinogen Kininogens Plasma Kallikrein BKB 2 Receptor
Renin
Substance P
neutral endopeptidase
Chymase
prolylendeptidase
Endothelin I ACE Angiotensin Converting Enzyme
Inactive Peptides
Angiotensin (1-7) Receptor 3 AT 3
Angiotensin I
Big endothelin Bradykinin
Vasodilation , release of nitric oxide, prostacyclin, and endothelium derived hyperpolarizing factor, inhibition of platelet adhesion, and inhibition of smooth muscle proliferation.
Kidney
ACE Inhibitors
Capillary
Vasodilation & potentiate bradykinin
Inhibition of
Adrenal Cortex Aldosterone Metabolsim
Angiotensin II
Angiotensin II Receptor 1 AT 1
Angiotensin II Receptor Aldosterone Secretion Angiotensin II Receptor Blockers
Systemic Vasoconstricition & expression of Plasminogen Activator Inhibitor-1 Angiotensin III Arginylaminopeptidase Glutamylaminopeptidase Angiotensin IV Angiotensin IV(3-8) Receptor 4 AT 4
Learning and memory
Posterior pituitary Vasopressin release Angiotensin II Receptor 2 AT 2
Sodium resorption from the kidney distal kubules Lumen Sodium Channel
Na +
Vasodialation & Apoptosis
Sodium Channel Modulators
Aldosterone Receptor
