Pathway Ska.docx

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Plak ateroma pembuluh darah koroner koyak/pecah

Terbentuk trombus

Trombus menyumbat pembuluh darah koroner

Pelepasan zat vasoaktif

Vasokontriksi pembuluh darah koroner

Aliran darah koroner berkurang

Iskemia miokard Jika pasokan O2 berhenti selama kurang lebih 20 menit

Metabolisme anaerob Penimbunan asam laktat Nyeri

Infark miokard Mekanisme mempertahankan curah jantung dan perifer Refleks simpatik vasokontriksi sistemik retensi Na dan air

Hipoksia selular Gangguan kontraktilitas miokard Preload menurun Peningkatan tekanan ventrikel kiri

Penurunan curah jantung

Kongesti pulmonal Tekanan hidostatik>> tekanan osmotik Tansdusi cairan ke intersisiel

Odema abdomen dan ekstermitas Kelebihan volume cairan

Perembesan cairan ke alveoli Edema paru Gangguan pertukaran gas

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