Brand name: Metformin Generic name: Metformin HCl Indication: Management of type 2 DM Drug classification: Antidiabetic, Biguanides Mechanism of action: decreases hepatic glucose production, decreasing intestinal absorption of glucose and improves insulin sensitivity (increases peripheral glucose uptake and utilization) Dosage: 500mg bid Special precaution: concurrent renal disease, geriatric patients, chronic alcohol abuse, serious medical conditions, patients undergoing stress, hypoxia, hyperthyroidism, pregnancy, lactation, children <10 yrs old Pregnancy risk category: C Adverse reaction: GI: abdominal bloating, diarrhea, nausea, vomiting, unpleasant metallic taste Endo: hypoglycemia others: lactic acidosis, decreased cobalamin level Contraindicated in: hypersensitivity, metabolic acidosis, dehydration, sepsis, hypoxemia, hepatic impairment, excessive alcohol use, renal dysfunction Form: Tablet 400 mg
Nursing responsibilities: Assess clients diseases such as renal disease and liver diseases Monitor client’s glucose level Ask client whether his an alcoholic or not