Generic name T rade name Lanoxin digoxin
Classification Route T ime/Frequency Normal Dosage- PO digitalizing doseantiarrhythmics PO or IV 0.75-1.5mg IV digitalizing dose0.5g-1 mg Indications-Tx of CHF.Tachyarrhythm ias:atrial fibrillation n atrial Contraindications/warnings/interactions - ventricular fibrillation or in flutter(slows ventricular rate),paroxysm al atrial tachycardia. patients with a known hypersensitivity to digoxin.
M echanism of action-Increases the force of myocardial Common side effects-fatigue, headache, bradycardia, anorexia, contraction.prolongs refractory period of the AV nausea, vomiting. node.decreases conduction through the SA n AV nodes. Lab value alterations- serum electrolyte levels(esp. potassium, magnesium, calcium) n renal n hepatic functions periodically during therapy Nursing Considerations-monitor apical pulse for 1 full min before administering, n significant changes in rate, rhythm quality of pulse. Assess for falls risk(digoxin fall risk) n implement prevention Interactions with other patient drugs, OT C, or herbal strategies per facility protocol. medicines-antacids, or Kaopectate, alprazolam (Xanax), Toxicity n overdose: therapeutic serum digoxin levels range from 0.5-2 cancer medications, clonidine (Catapres), supplements or medications that contain calcium, diuretic (water pill), such asmg/ml. Serum levels may be drawn 6-8 hr after a dose is administered. spironolactone (Aldactone, Aldactazide), amphotericin B, cholestyramine (Questran, Prevalite), epinephrine (EpiPen), Why would you hold or not giveEvaluation- Dec. in severity of guanabenz (Wytensin) or guanfacine (Tenex), indomethacin this med?withhold dose n notify CHF. Increase in cardiac output, (Indocin), isoproterenol (Isuprel), itraconazole (Sporanox), physician if pulse rate is <60 bpm Dec. in ventricular response in levothyroxine, methyldopa (Aldomet), metoclopramide (Reglan), atrial tachyarrhythmias. neomycin , rifampin , sulfasalazine (Azulfidine), an antibiotic Termination of paroxysmal atrial such as erythromycin, clarithromycin (Biaxin), or tetracycline, tachycardia. beta-blockers, calcium channel blockers, decongestant cold or allergy medicine, or nasal sprays, a heart rhythm medication, steroids