Drug Study In Rmc

DRUGS 1. Amikacin IV

MECHANISM OF ACTIONS Inhibits production of bacterial protein, causing bacterial cell death.

INDICATIONS Treatment of infections caused by susceptible strains of microorganism s, especially gram-negative bacteria.

CONTRAINDICATI ONS A history of hypersensitivity to Amikacin is a contraindication for its use. A history of hypersensitivity or serious toxic reactions to aminoglycosides may contraindicate the use of any other aminoglycoside because of the known crosssensitivities of patients to drugs in this class.

ADVERSE EFFECTS This medication may cause nausea, vomiting or weakness as your body adjusts to the medication. If these effects continue or become severe, inform your doctor. This medication can cause hearing loss or kidney damage especially if used in high doses or for prolonged periods of time. It is important the proper dose be used. The site where the injection is given may be red and irritated for a few days. Notify your doctor if the irritation continues or becomes worse. Notify your doctor immediately if you develop: dizziness, ringing in the ears, hearing loss, skin rash, difficulty breathing, difficult or painful urination,

NURSING CONSIDERATIONS ➢ Patients should be counseled that antibacterial drugs including Amikacin should only be used to treat bacterial infections. ➢ Patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. ➢ Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and

2. PenicillinG Benzathin e

Inhibits cell wall synthesis during bacterial multiplication

Moderate to severe systemic infections

muscle twitching. If you notice other effects not listed above, contact your doctor or pharmacist.

will not be treatable by Amikacin or other antibacterial drugs in the future.

Contraindicated to patient hypersensitive to drug.

This medication may cause mild diarrhea, stomach upset, nausea, vomiting or irritation at injection site during the first few days as your body adjusts to the medication. If these symptoms persist or worsen, inform your doctor. Notify your doctor immediately if you develop: watery diarrhea, stomach cramps, fever, unusual bleeding or bruising, yellowing of the eyes or skin, unusual tiredness or weakness. In the unlikely event you

➢ Before giving drug, ask patient, about allergic reaction to drugs. ➢ Tell patient to report adverse reaction to drugs. ➢ Assess medical history, especially of: kidney disease, stomach/intestina l diseases, allergies (especially allergies to penicillins, other antibiotics, procainamide, ester-type anesthetics such

3. Salbutamol Sulfate Solution for Nebulization 2.5 mg / 2.5 ml

Salbutamol is a beta2 adrenoreceptor agonist. At therapeutic doses it acts on the beta2 adrenoreceptors of bronchial muscle, with little or no action in beta1 adrenoreceptors of cardiac muscle.

Salbutamol is used as a bronchodilator for the symptomatic relief of bronchospasm in obstructive airway diseases like bronchial asthma, emphysema, and chronic bronchitis. In moderate to severe or unresponsive asthma, salbutamol is given via a nebulizer.

have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: wheezing, difficulty breathing, skin rash. ➢ Hypersensiti vity to the drug or any of its components ➢ Thyrotoxico sis ➢ Threatened abortion during the first and second trimesters of pregnancy. ➢ There is no definite proof as to the safety of the drug to the fetus in the early stages of pregnancy

Tachycardia Palpitations Flushing Fine tremors of skeletal muscles, particularly of the hands ➢ Feeling of ➢ ➢ ➢ ➢

as lidocaine, PABA products such as methylparaben

➢ Administer with caution to patients with cardiovascular disease. ➢ Administer with caution in patient with convulsive disorders, hyperthyroidism or diabetes mellitus. ➢ Anginal pain maybe precipitated in patients with angina pectoris.

nervousness and tension ➢ Headaches ➢ Muscle cramps.

➢ Administer with caution to patients taking other symphatomimetic drugs. ➢ Instruct patients receiving treatment at home to seek medical advice if usual relief is not obtained after the usual dose. THE DOSE SHOULD NOT BE INCREASED. ➢ Adjustment of dose and frequency of administration should only be by medical advice. ➢ Give cautiously to patients with hypokalemia.