Drug Study

Chapter III – IMPLEMENTATION A. Medical Management Drug

METACLOPARAMIDE

Generic Name: PLASIL

Classification

Antiemetics

Doe, Route, Frequency

10-20mg, P.O., 30 mins.

Mechanism of action

Stimulates motility of upper GI tract Increase lower esophageal sphincter tone & blocks dopamine receptors at the chemoreceptor trigger zone

Contradiction

Contraindicated in patient’s hypersensitivity to drug & in those with pheochromocytom a or seizure disorders. Contraindicated in patient’s whom stimulation of GI motility might be dangerous

Side effects

Nursing Responsibilities

Fever, Tell patient to avoid headache, activities that require dizziness alertness for 2 hours after dose. Stay with the patient while drinking the drug

Drug

Ranitidine

Generic name: Zantac

Classificatio n

Doe, Route, Frequenc y

Mechanism of action

Contradiction

Anti-ulcer drugs

150 mg, P.O b.i.d

Competitively inhibits action of histamine on the H2 at receptor sites of parietal cells, decreasingly gastric acid secretion.

Contraindicated in patient hypersensitive to drug & those with acute porphyna

Or 300mg daily at bedtime

Use cautiously in patients with hepatic dysfunction. Adjust dosage in patients with impaired renal function

Side effects

Dry mouth, headache, vomiting, nausea

Nursing Responsibilities

Instruct patient on proper use of OTC preparation as indicated

Drug

H NBB Generic brand: Buscopan

Classificatio n

Doe, Route, Frequenc y

Mechanism of action

Contradiction

Side effects

Nursing Responsibilities

Drug

Classificatio n

Doe, Route, Frequenc y

Mechanism of action

Contradiction

Side effects

Nursing Responsibilities