Deber.docx

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Porque al reducir el punto de corte de 50.000 UFC a 10.000 UFC la sensibilidad disminuye? Titulo: atractivo, 15 words, describe population, single paragraph. Autor: Leah Tzimenatos, emergency medicina and pediatrics Abstract: clear, objectives, methods (cocepts of UTI, two analysis, definition of POSITIVE urinalysis {LE, pyuria, nitrites}), results (population, S, E, NPV, PPV) and conclusions. Variable independiente – Variable resultado (dependiente) – Tipo analisis estadistico - X2, Wicolson 5. Introduction: concepts are clear and understandable, catch attention, answers to why, it is interesting. *APP: reported test S 48% to 99% E 88-98% *Methods of urine collection: catheter vs nocatheter; dipstick +/- microscopy *Urinalysis: LE, nitrite, pyuria * Aim is clear. *It shows a background for describing the problem. *It is difficult to find the predictive and dependent variable 6. Methods: - exclusion – sepsis, ho prematutiry, comorbid conditions, recent ATB use, bacteriemia wo UTI, concurrent UTI - inclusion - (+) test with catheterization or suprapubic aspiration. - ETICS: consent - Not mention about bias - Type of design: secondary analysis of a large, prospective cross-sectional study (prevalence) - X2 square: cathegorical infants w & w/o UTIs & infants w & w/o bacteremia. - Wilcoxon rank: cuantitativas continuas AP NP - Program:SAS version 9.4 - Explanation of 4778 – 631= 4147 7. RESULTS:  Found accuracy S & E of urinalysis in infants of 60 days and younger.  High and perfect S and E in children with UTIs +/- bacteremia.  The presentation of details are clear even though PPV ad NPV appear just in the table.  The used text and tables. Use one diagram for explaining exclusion criteria.  They didn’t repeat information of methods.  They describe characteristic of the population in the tables, clearly 8. DISCUSION: V. INTERNA (S & E) present because population is intented to be homogeneous, less subjects of study. V. EXTERNA: VPP, NPV (high). Generalization to other subjects? Just for the NPV 9. CONCLUSIONS: The accuracy is expressed by high S, E. Theydont mention clearly the high NPV which represent an important indicator of external validity. The mention a clear, simple answer.