Clopidogrel (plavix)

INDEX Generic Name

Trade Name

clopidogrel

Plavix

NURS 2236 Clinical Form 3: Clinical Medications Worksheet (You will need to made additional copies of these forms) Classification Dose Route Time/Frequency antiplatelet agent 75mg PO Once daily

Peak Onset 3-7 days within 24 hr Why is your patient taking this medication?

Duration 5 days after d/c

Mechanism of action and indications Reduction of atherosclerotic events (MI, stroke, vascular death) in patients at risk for such events including recent MI, acute coronary syndrome (unstable angina/non-Q-wave MI), stroke, or peripheral vascular disease. Decreased occurrence of atherosclerotic events in patients at risk.

Interactions with other patient drugs, OTC, or herbal medicines (ask patient specifically) abciximab; eptifibatide; tirofiban; aspirin; NSAIDs; heparin; heparanoids; thrombolytic agents; ticlopidine; warfarin; phenytoin; tolbutamide; tamoxifen; torsemide; fluvastatin; Natural drugs: anise; arnica; chamomile; clove; fenugreek; feverfew; garlic; ginger; ginkgo; Panax ginseng.

Nursing Process - Assessment (Pre-administration assessment Vital signs; symptoms of stroke, peripheral vascular disease, MI; signs of thrombotic thrombocytic purpura;

For IV meds, compatability with IV drips and/or solutions

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity; pathologic bleeding (peptic ulcer, intracranial hemorrhage); lactation. Use cautiously in: Patients at risk for bleeding; history of GI bleeding/ulcer disease; severe hepatic impairment; pregnancy; children. Common side effects Depression; dizziness; fatigue; headache; epistaxis; cough; dyspnea; chest pain; edema; hypertension; GI bleeding; abdominal pain; diarrhea; dyspepsia; gastritis; pruritus; purpura; rash; bleeding; neutropenia; thrombotic thrombocypenic purpura; hypercholesterolemia; arthralgia; back pain; fever; hypersensitivity reactions. Lab value alterations caused by medicine

Be sure to teach the patient the following about this medication Notify doctor if fever, chills, sore throat, or unusual bleeding and bruising occurs. Surgery; OTC medications containing aspirin or NSAIDs.

Assessment Why would you hold or not give this med? thrombocytopenia; microangiopathic; hemolytic anemia; neurologic findings; renal dysfunction; fever. Pathologic bleeding.

Evaluation Check after giving Prevention of stroke, MI, and vascular death in patients at risk