Brain Actinomycosis

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Brain Actinomycosis: Report of one case Jorge L. Rivera-Rodriguez, MD, Eugenia Zurita,CNS. Hospital General de Acapulco SSA México

Introduction Actinomycosis is an infection primarily caused by the bacterium Actinomyces israelii. Actinomycosis located in the central nervous system is an extremely uncommon event. It may affect immunocompetent or immunodefficient subjects. It is commonly misdiagnosed in routine imaging studies

Medical History Female, 32 y.o. Previously healthy. Recent onset of right extremities partial motor epilepsy. A Brain scan showed: left parietal 2 cm solid mass, IV contrast inhancing, important periferic oedema. Negative Chest Xray No neck masses.

Preoperative Scan

Differential Diagnosis Primary tumor. Brain Abscess. Granuloma.

A parietal craniotomy and total resection of the lesion was performed. Hystopathological report: Brain Actinomycosis

Postoperative Brain Scan

No additional antimycrobial therapy was given. Total neurological recovery. Clean long term scanning. Seizure free without antiepileptic drugs at present.

Conclusions Brain Actinomycosis is a rare entity and should be considered in any brain mass differential diagnosis. Total surgical removal without long term antimycrobial therapy seems to be effective, but more studies should be performed.

Bibliography Allen HA, Scatarige JC, Kim MH. Actinomycosis: CT findings in 6 patients. Am J Radiol 1987;149:1255-1258. Bartels LJ, Vrabec DP. Cervicofacial actinomycosis. Arch Otolaringol 1978;104:705-708. Bennhoff DF. Actinomycosis: diagnostic and therapeutic considerations and a review of 32 cases. Laryngoscope 1984;94:1198-1217. Dos Santos Junio EA, Pitella JE. Actinomycosis ot the brain: case report. Arq Neuropsiquiatr.1999;57(3A):689-694. Harvey JC, Cantrell JR, Fisher AM. Actinomycosis: its recognition and treatment. Ann Intern Med 1957;46:868-885. Lotier J, Venet C, Chambonniere ML. Multiple actinomycosis brain abscesses. Presse Med.2004;33(5):318-320. Macfarlane DJ,Tucker LG, Kemp LJ. Treatment of recalcitrant actinomycosis with cyprofloxacin. J Infect 1993;27:177-180. Norman JE. Cervicofacial actinomycosis. Oral Surg Oral Med Oral Pathol 1970;29:735-744. Rankow RM, Abraham DM. Actinomycosis: masquerader in the head and neck. Ann Otol Rhinol Laryngol 1978;87:230-237. Smego RA. Actinomycosis of the central nervous system. Rev Infect Dis 1987;9:855-865 Sudkaker, Selvin S, Rose JJ. Short term treatment of Acinomycosis two cases and a review. Clin Infect Dis 2004;2:444-448.

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