The Muscular System Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Functions and Types of Muscles o
Smooth Muscle • • • • •
Located in the walls of hollow organs and blood vessels Involuntary contraction Moves materials through organs and regulates blood flow Cylindrical cells with pointed ends Each cell is uninucleate
Functions and Types of Muscles o
Cardiac Muscle • • • • •
Forms the heart wall Fibers are uninucleated, striated, tubular, and branched Fibers interlock at intercalated disks, which permit contractions to spread quickly throughout the heart Contraction does not require outside nervous stimulation Nerves do affect heart rate and strength of contraction
Functions and Types of Muscles o
Skeletal Muscle • • •
Fibers are tubular, multinucleated, and striated Make up muscles attached to the skeleton Contraction is voluntary
Functions of Skeletal Muscles • • • • •
Support the body Make bones and other body parts move Help maintain a constant body temperature Assists movement in cardiovascular and lymphatic vessels Help protect bones and internal organs, and stabilize joints
Connective Tissue Coverings of Skeletal Muscle •
Endomysium
•
Thin layer of areolar connective tissue Surrounds each skeletal muscle fiber
Perimysium – surrounds bundles of muscle fibers (fascicles) Epimysium
•
Layer that surrounds the entire muscle Becomes part of the fascia (separates muscles from each other) Collagen fibers extend from epimysium to form tendons that attach muscles to bone
Microscopic Anatomy o
Muscle fiber components • •
Sarcolemma – plasma membrane Sarcoplasm – cytoplasm
•
Contains glycogen that provides energy for muscle contraction Contains myoglobin which binds oxygen until needed
Sarcoplasmic reticulum – endoplasmic reticulum T (transverse) tubules
•
Formed by the sarcolemma penetrating into the cell Come into contact with expanded portions of the sarcoplasmic reticulum
Microscopic Anatomy o
Myofibrils and Sarcomeres • •
Myofibrils run the length of the muscle fiber Composed of numerous sarcomeres Extends between two vertical Z lines Contains two types of protein myofilaments
Thick filaments – made up of myosin Thin filaments – made up of actin, tropomyosin, and troponin
I band contains only thin filaments A band in the center of the sarcomere contains thick and thin filaments H zone in the center of the A band has only myosin filaments
Microscopic Anatomy o
Myofilaments •
Thick filaments
•
Composed of several hundred of molecules of myosin Myosin molecules end in a cross-bridge
Thin filaments
Two strands of actin Double strands of tropomyosin coil of each actin strand Troponin occurs at intervals on the tropomyosin strand
Microscopic Anatomy •
Sliding Filament Model
Occurs when sarcomeres shorten (during muscle contraction) Actin filaments slide past the myosin filaments Thick and thin filaments remain the same length
Contraction of Skeletal Muscle o
Neuromuscular junction •
Axon terminals
•
Come into close proximity to the sarcolemma Have vesicles that contain acetylcholine (Ach)
Synaptic cleft – a small gap that separates the axon from the sarcolemma
Fig 7.4
Contraction of Skeletal Muscle o
Steps involved in skeletal muscle contraction • • • • • •
Nerve signal arrives at the axon terminal The synaptic vesicles release Ach Ach binds to receptors on the sarcolemma The sarcolemma generates a signal that travels down the T tubules to the SR The SR releases calcium Calcium from the SR causes the filaments to slide past one another
Contraction of Skeletal Muscle o
The Role of Actin and Myosin •
Myosin binding sites on actin molecules
•
Covered by tropomyosin when muscle is relaxed Released calcium combines with troponin and myosin binding sites are exposed
Cross-bridges of myosin have two binding sites
One site binds to ATP Second binding site binds to actin
Contraction of Skeletal Muscle o
Energy for Muscle Contraction •
ATP present before strenuous exercise only lasts a few seconds Muscles acquire new ATP in three ways
•
Creatine phosphate breakdown Cellular respiration Fermentation
Contraction of Skeletal Muscle Creatine Phosphate Breakdown
Does not require oxygen (anaerobic) Regenerates ATP by transferring its phosphate to ADP Fastest way to make ATP available to muscles ATP produced only lasts about 8 seconds
Contraction of Skeletal Muscle •
Cellular Respiration
Usually provides most of a muscle’s ATP Uses glucose from stored glycogen and fatty acids from stored fats Required oxygen Myoglobin can make oxygen available to muscle mitochondria Carbon dioxide and water are end products Heat is a by-product
Contraction of Skeletal Muscle •
Fermentation
Anaerobic process Produces ATP for short bursts of exercise Glucose is broken down to lactate (lactic acid)
Contraction of Skeletal Muscle o
Oxygen Debt • •
Occurs when muscles use fermentation to supply ATP Requires replenishing creatine phosphate supplies and disposing of lactic acid
Contraction of Smooth Muscle Smooth muscle fibers contain thick and thin filaments
o • •
o o o
Filaments are not arranged into myofibrils that create striations Thin filaments are anchored to the sarcolemma or dense bodies
When contracted, the elongated cells become shorter and wider Contraction occurs very slowly Contractions can last for long periods of time without fatigue
Muscle Responses in the Laboratory o
All-or-none law – a muscle fiber contracts completely or not at all A whole muscle shows degrees of contraction
o •
Muscle twitch – a single contraction that lasts only a fraction of a second
• •
Latent period Contraction period Relaxation period
Summation – increased muscle contraction Tetanic contraction – maximal sustained contraction
Muscular Responses Threshold Stimulus • minimal strength required to cause contraction Recording a Muscle Contraction • twitch • latent period • period of contraction • period of relaxation • refractory period • all-or-none response
Summation • process by which individual twitches combine • produces sustained contractions • can lead to tetanic contractions
Muscle Responses in the Laboratory o
Fatigue •
Muscle relaxes even though stimulation continues Reasons for fatigue
•
ATP is depleted Accumulation of lactic acid in the sarcoplasm inhibits muscle function ACh may become depleted
Muscle Responses in the Body o
Motor unit • •
o
A nerve fiber together with all of the muscle fibers it innervates Obeys the all-or-none law
Recruitment • •
o
As the intensity of nervous stimulation increases, more motor units are activated Results in stronger muscle contractions
Tone • •
Some muscle fibers are always contracting Important in maintaining posture
Muscle Responses in the Body o
Athletics and muscle contraction •
Size of muscles
•
Atrophy – a decrease in muscle size Hypertrophy – an increase in muscle size
Slow-twitch fibers (Type I fibers)
Tend to be aerobic Have more endurance Have many mitochondria Dark in color because they contain myoglobin Highly resistant to fatigue
Muscle Responses In the Body •
Fast-twitch fibers (Type II fibers)
Tend to be anaerobic Designed for strength Light in color Have fewer mitochondria, little or no myoglobin, and fewer blood vessels than fast-twitch fibers Vulnerable to accumulation of lactic acid and can fatigue easily
Skeletal Muscles of the Body o
Basic Principles • • • • •
Origin – attachment of a muscle to the immovable bone Insertion – attachment of a muscle to the bone that moves Prime mover – muscle that does most of the work in a movement Synergist – muscles that assist the prime mover Antagonists – muscles that work opposite one another to bring about movement in opposite directions
Skeletal Muscles of the Body o
Naming Muscles • • • • • • •
Size Shape Direction of fibers Location Attachment Number of attachments Action
Skeletal Muscles of the Body
o Muscles of the Head • Muscles of Facial Expression
Frontalis Orbicularis oculi Orbicularis oris Buccinator Zygomaticus
• Muscles of Mastication
Masseter muscles Temporalis muscles
Fig 7.13
Skeletal Muscles of the Body o
Muscles of the Neck •
Swallowing
•
Tongue and buccinators Suprahyoid and infrahyoid muscles Palatini muscles Pharyngeal constrictor muscles
Muscles that move the head
Sternocleidomastoid Trapezius muscles
Skeletal Muscles of the Body o
Muscles of the Trunk •
Muscles of the thoracic wall
•
External intercostal muscles Diaphragm Internal intercostal muscles
Muscles of the abdominal wall
External and internal obliques Transversus abdominis Rectus abdominis
Skeletal Muscles of the Body Muscles of the Shoulder (Table 7.4)
o
Muscles that move the scapula
•
Trapezius Serratus anterior
Muscles that move the arm
•
Deltoid Pectoralis major Latissimus dorsi Rotator cuff muscles
Supraspinatus Infraspinatus Teres minor Subscapularis
Fig 7.15
Skeletal Muscles of the Body o
Muscles of the Arm • • •
o
Biceps brachii Brachialis Triceps brachii
Muscles of the Forearm • •
Flexor carpi and extensor carpi Flexor digitorum and extensor digitorum
Tab. 7.4
Skeletal Muscles of the Body o
Muscles of the Hip and Lower Limb (Table 7.5) •
Muscles that move the thigh Iliopsoas Gluteus maximus Gluteus medius Adductor group muscles
Pectineus Adductor longus Adductor magnus Gracilis
Skeletal Muscles of the Body •
Muscles that move the leg Quadriceps femoris group
Rectus Vastus Vastus Vastus
femoris lateralis medialis intermedius
Sartorius Hamstring group
Biceps femoris Semimembranosus Semitendinosus
Skeletal Muscles of the Body •
Muscles that move the ankle and foot
Gastrocnemius Tibialis anterior Fibularis longus Fibularis brevis Flexor and extensor digitorum longus
Tab. 7.5
Effects of Aging o o o
Muscle mass and strength tend to decrease Endurance decreases Exercise at any age can stimulate muscle buildup
Homeostasis o o o o o o o
Cardiac muscle contraction forces blood into the arteries and arterioles Smooth muscle in arteries and arterioles help maintain blood pressure Smooth muscle contraction moves food along the digestive tract and assists in the voiding of urine Skeletal muscles protect internal organs and stabilizes joints Skeletal muscles are active during breathing Heat produced by skeletal muscle contraction helps maintain normal body temperature Skeletal muscle contraction allows us to relocate our bodies