Reasons For Opening Arogya.doc

Pandeypur, Varanasi-221 002, INDIA Ph. 0542-3252795 REASONS FOR OPENING “Arogya AYURVEDA & PANCHKARMA HOSPITAL” Reasons for Running the Center 1. “WHO Alma Ata Declaration 1978” - “Health For All” - The target of health for all cannot be achieved without the help of Traditional System of medicine and total resources. 2. “Report of Joint Study Group, ICSSR and ICMR, 1981” - Alternative model of health care services - Within the health sector, our most important recommendation is that the existing exotic, top-down, elite-oriented, urban-biased, centralized and bureaucratic system which over-emphasizes the curative aspects, large urban hospitals, doctors and drugs should be replaced by the alternative model of health care services in a planed and phased manner by 2000 AD. This alternative model is strongly rooted in the community, provides adequate, efficient and equitable referral services, integrates promotive, preventive and curative aspects, and combines the valuable elements in our culture and tradition with the best elements of the western system. It is also more economical and cost effective. 3. “The Awaji Declaration - WHO - 13th September 2000” - “We the international participants at the Awaji International symposium on traditional medicine, celebrate the people-led movement in health care and the spirit of progress made in Awaji and declare the importance of traditional medicine in creating and nurturing health for the people of the world, and request all people to promote the use of traditional medicine and integrate it into their health systems to benefit those in need, through a satisfactory method of health care that builds on time tested cultural knowledge to alleviate suffering and to assist people in establishing balance in their lives in a closer relationship with nature and for the health of the Earth, our Mother.”

4. The report "Healthy People 2000" by U.S. Department of Health and Human service lays emphasis for investigating alternatives to current diseases. It says that health of the people should bee measured by more than deaths rates. It should include good and improved quality of life, reduced suffering, illness and disability. This is done by Panchakarma therapy. 5. Two resolutions concerning Traditional Medicine, adopted by WHO Regional Committee, laying stress to in corporate the services of alternative systems of medicine, specially in the area of chronic degenerative diseases and evaluating the safety and efficacy of traditional medicine, based on the concepts of both modern and traditional systems of medicine. Goals of Arogya Ayurveda & Panchkarma 1. To gather appropriate scientific data for rational use and further development of therapy. 2. To eliminate the myths regarding Panchkarma therapy. 3. To promote Panchkarma therapy by promoting the therapy in clinical Practice. 4. To help promotion of clinical research on the therapy over different incurable diseases. Objectives of Arogya Ayurveda & Panchkarma Hospital (1) To Promote Panchkarma therapy in healthy individuals for promotion of good health. (2) To emphasize importance of biopurificatory measures in diseased persons for complete cure, especially in chronic diseases. (3) To provide important documents and clinical data for research in Panchkarma. (4) To identify clinical and bio - chemical parameters for monitoring and evaluating the effects of Panchkarma in various diseases. (5) To help Ayuvedic clinicians in routine practice.

RESEARCH AREAS AND METHODOLOGY IN PANCHKARMA Studies conducted at Arogya Ayurveda & Panchkarma Hospital INTERNAL SNEHAN (1) To assess the pharmaco-kinetics of medicated oil and plain oil i.e. absorption, assimilation, excretion, and its biological role. (2) To understand role of different oils in different diseases. (3) Clinical comparison between therapeutic effect of Plain Ghrit and Medicated Ghrit. (4) It is learned that plant sterols have the tendency to reduce cholesterol levels, thus oils like Taila (sesame oil) Taila may be beneficial in obesity. CLINICAL AND BIOMARKERS OF SNEHAN(1) Changes in appetite, bowel habits and fecal features. (2) General feeling of patient viz. malaise, heaviness and feeling of stickiness of skin. (3) Lipid profile assessment before and after therapy. (4) Gastric juice analysis for assessment of: (a) Free and total acid levels (b) Mucin analysis (c) Pepsin and pepsinogen (5) Intestinal juice analysis (a) Trypsin (b) Lipase activity (6) Assessment of blood histamine and immunoglobulins, before and after therapy. (7) Plain X-ray Abdomen/USG Abdomen to see the gastric dilatory effect of high dose of lipid intake. Research Areas: EXTERNAL SNEHAN (1) To assess the advantages of using different oil in different diseases. (2) To assess advantage of massaging with oil and with plain hands. (3) Advantage of hot fomentation after oil massage. (4) Comparative Study of therapeutic effect of medicated fomentation and hot Plain fomentation. (5) To assess that the oleation and sudation therapy brings the Doshas (Toxins, free radicals, antigens, virus and bacteria etc.) To the G.I.tract for Vaman and Virechan.

Bio - Clinical markers which are intended to be used at Arogya Ayurveda & Panchkarma Hospital Vamana (a) Clinical signs of proper Vaman. (b) Muco polysaccharide estimation - As proved by R.S. Singh and R.H. Singh, the muco polysaccharide content of vomitus could be taken as a standard marker for estimating the aggravated Kapha Dosa in Vaman therapy. (c) Blood Histamine estimation - Before and after Vaman therapy, it has been observed that blood histamine level significantly reduces immediately after Vaman and remains low even after several months of Vaman therapy, suggesting an elimination of histamine in the vomiting through Gut dialysis. The sustained reduction of blood histamine level indicate, lowered physiological demand of histamine in the system due to purified bio-interior (Mast Cell Stabilizing Effect) (d) Lipid profile estimation - Since, it is indicated in obesity, the lipid profile changes before and after the therapy should be observed. (e) Long term benefits by estimating: (i) Immunoglobulin assessment, (IGg levels), before and after therapy. (ii) Reduction in free radicals by evaluating serum SOD ( Super oxide dismutase analysis). (iii) Changes in Neuro-endocrine hormones - Thyroid profile, ACTH, Androgens and Insulin levels. BIO - CLINICAL MARKERS OF VIRECHANA (1) Assessment of Procedural Success: (i)

No. of bouts (Vegas)

(ii) Quantity of faeces

Good

Moderate

Mild

15 - 30

10 - 15

5 -10

2.5 - 3.0

1.5 - 2.0

1.0 - 1.5

(Monaki) in liters (iii) Order of contents (Antaki) (iv) Symptoms (laingiki)

Kapha/mucin

Pitta

Vata

in the end Sings and symptoms of proper purgation

(2) Estimation of Stercobilinogen : Rate of elimination of stercobilinogen in the faeces can be taken as an index of elimination of stool (Mala) Pitta during Virechan (Singh and Singh 1974) (3) Gradation of cure of specific disease by. (i) Clinical symptom grading, according to disease (ii) Relevant biochemical analysis for estimating therapeutic effect. (4) Long term benefits can be assessed by. (i) Estimation of Immunoglobulin IGg levels before and after therapy. (ii) Reduction in levels of free radicals by super oxide dismutase (SOD) analysis (iii) Changes in Neuro-endocrine hormones, thyroid profile, ACTH androgens and insulin levels etc. Complications of Virechana: 1. Adhmana (Tympanitis)

2. Parikartika (Cutting pain)

3. Parisrawa (Dischrage)

4. Hrdgraha (Cardiac discomfort)

5. Gatragraha (Stiffness)

6. Jiwadana (haemorrhage)

7. Vibhrama (Confusion)

8. Stambha (Stiffness)

9. Klama (Neurasthenia)

10. Other Complication

Here tympanitis, dischrage, cardiac discomfort, Gatragraha (stiffness), confusion, neurasthenia, & other complication are due to inadequate Virechana & cutting pain, haemorrhage, stiffness are due to excess Virechana. Bio - Clinical Markers of Vasti: (i) Proper symptoms of good Vasti (ii) Estimation of Immune - globulin levels before and after treatment (iii) Free Radical estimation (iv) Role of Neurotransmitters to evaluate the long term effect of Vasti Vasti Research Area: It is now being proved that enteric nervous system is a collection of neurons that apart from influencing the GIT also influence the Autonomic nervous system there by producing systemic effects. Thus there is need to know -

(1) Effect of Vasti on enteric nervous system. (2) Its biophysical effect on the colon, viz Intracolonic pressure, Changes in viscosity and PH etc. (3) Osmosis/ Dialysis of toxins. (4) Changes in bacterial flora of the colon and its neuro - bio - attributes. (5) To monitor the retention time of Vasti. (6) Analysis of expelled material in Vasti. (7) Medicinal effect of Vasti. Bio - clnical Markers of Nasaya: (1) Number of sneezing bouts. (2) Quantity and Quality of sneezed material. (3) Symptomatic relief, it any by suitable grading scales. (4) Disease specific clinical and investigatory evaluation. The objective of Samsarjan Krama is to restore digestive power through specific dietary schedule. After Samsarjan Krama not only Appetite increases but also absorptive and assimilatory functions of G.I. tract is improved. Bio-clinical evaluation: D-Xylose Excretion test The excretion of D-Xylose is increased after Samsodhan and Samsarjan procedure which directly signifies the improved state of absorption of G.I. tract.