Potential Protective Effect Of Vitamin C On Carcin...[eur J Surg Oncol. 1992] - Pubmed Result
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1: Eur J Surg Oncol. 1992 Jun;18(3):275-81.
Potential protective effect of vitamin C on carcinogenesis caused by nitrosamine in drinking water: an experimental study on Wistar rats. Kessler H, Husemann B, Wagner W.
Related Articles [The effect of subcutaneous nitrosamine injections on the origin of tumors of the liver and their inhibition by vitamin C] [Ze ntr alb lChir. 1988] [Experimental development of carcinoma in rats caused by N-nitrosopiperidine with vitamin C] [Ze ntr alb lChir. 1991]
Surgical Hospital, University of Erlangen-Nürnberg, Germany.
In an experiment with Wistar rats the question of whether oral vitamin C application has a protective effect in liver carcinogenesis caused by N-nitrosodiethylamine in drinking water (n = 104) was studied. When comparing four groups (without carcinogen, with carcinogen and carcinogen plus vitamin C alternately and concomitantly) significant statistical differences in the linear regression were noted. Ninety per cent of the rats developed hepatocellular carcinomas when only carcinogen was administered whereas the rate with additional administration of vitamin C alternately and concomitantly was 68% and 55%, respectively. Without carcinogen no tumour developed. The results suggest that vitamin C may delay the development of liver cancer upon oral administration of N-nitrosodiethylamine. The explanation for this fact is still hypothetical.
NTP Toxicology and Carcinogenesis Studies of Pyridine (CAS No. 110-86-1) in F344/N Rats, Wistar Rats, and B6C3F1[Nat Mice (Drinking Water Studies). l To xicol Pr ogr am Tech Rep Ser. 2000] Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis. [Oncol ogy. 2004] Effects of green tea catechins in a rat multi-organ carcinogenesis model. [Ca rcinog enesis. 1993] » See All...
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PMID: 1318851 [PubMed - indexed for MEDLINE]
Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body. Source: AHFS Consumer Medication Information
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Potential protective effect of vitamin C on carcinogenesis caused by nitrosamine in drinki... Characterization of a new malignant human T-cell line (PFI-285) sensitive to ascorbic acid... Dietary vitamins A, C, and E and selenium as risk factors for cervical cancer.
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1: Eur J Surg Oncol. 1992 Jun;18(3):275-81.
Potential protective effect of vitamin C on carcinogenesis caused by nitrosamine in drinking water: an experimental study on Wistar rats. Kessler H, Husemann B, Wagner W.
Related Articles [The effect of subcutaneous nitrosamine injections on the origin of tumors of the liver and their inhibition by vitamin C] [Ze ntr alb lChir. 1988] [Experimental development of carcinoma in rats caused by N-nitrosopiperidine with vitamin C] [Ze ntr alb lChir. 1991]
Surgical Hospital, University of Erlangen-Nürnberg, Germany.
In an experiment with Wistar rats the question of whether oral vitamin C application has a protective effect in liver carcinogenesis caused by N-nitrosodiethylamine in drinking water (n = 104) was studied. When comparing four groups (without carcinogen, with carcinogen and carcinogen plus vitamin C alternately and concomitantly) significant statistical differences in the linear regression were noted. Ninety per cent of the rats developed hepatocellular carcinomas when only carcinogen was administered whereas the rate with additional administration of vitamin C alternately and concomitantly was 68% and 55%, respectively. Without carcinogen no tumour developed. The results suggest that vitamin C may delay the development of liver cancer upon oral administration of N-nitrosodiethylamine. The explanation for this fact is still hypothetical.
NTP Toxicology and Carcinogenesis Studies of Pyridine (CAS No. 110-86-1) in F344/N Rats, Wistar Rats, and B6C3F1[Nat Mice (Drinking Water Studies). l To xicol Pr ogr am Tech Rep Ser. 2000] Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis. [Oncol ogy. 2004] Effects of green tea catechins in a rat multi-organ carcinogenesis model. [Ca rcinog enesis. 1993] » See All...
Patient Drug Information
PMID: 1318851 [PubMed - indexed for MEDLINE]
Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body. Source: AHFS Consumer Medication Information
Recent Activity Turn Off
Clear
Potential protective effect of vitamin C on carcinogenesis caused by nitrosamine in drinki... Characterization of a new malignant human T-cell line (PFI-285) sensitive to ascorbic acid... Dietary vitamins A, C, and E and selenium as risk factors for cervical cancer.
Display
AbstractPlus
Show
20
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