Inhibition Of Benzo(a)pyrene Carcinogenesis In Rat...[j Cancer Res Clin Oncol. 1980] - Pubmed Result
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1: J Cancer Res Clin Oncol. 1980;97(1):91-6.
Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C.
Related Articles Inhibition of benzo(a)pyrene-induced carcinogenesis by vitamin C alone and by vitamin C/vitamin E and selenium/glutathione. [Biol Tr ace El em Res. 2003]
Kallistratos G, Fasske E. The s.c. infection of 10 mg benzo(a)pyrene dissolved in 1 ml tricaprylin induced in Wistar rats local malignant tumors, such as fibrosarcoma, rhabdomyosarcoma, and polymorph cell sarcoma. The growth of the tumors was relatively rapid, reaching weights of 140-155 g before rats died 142-168 days after the administration of the carcinogen. On the contrary, under the same experimental conditions, high doses of Vitamin C about 525 mg/day/rat administered orally in drinking water (total amount of Vitamin C 55 g/rat corresponding to 40% of their body weight ) inhibited to a great extent the benzo(a)pyrene carcinogenesis. Only one slowly growing rhabdomyosarcoma (13 g of weight) was developed showing characteristic damage of malignant cells and partial replacement of the neoplastic area with granuloma tissue. The significance ov Vitamin C for cancer prevention and treatment is discussed.
The paradoxical effect of vitamin C on benzo[a]pyrene-induced tumors and malignancy. [Natu rwisse nschaften. 1984] Dose-dependent effect of trichloropropene oxide on benzo[a]pyrene carcinogenesis. [JCancer ResClin Oncol. 1980] Review Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum [I ntannuum JT oxicol.fruit 2007] Review Prolongation of the survival time of tumor bearing Wistar rats through a simultaneous oral administration of vitamins C + E and selenium [ Pro gClinwith Bi ol Res. 1988] » See Reviews...
PMID: 7400211 [PubMed - indexed for MEDLINE]
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Patient Drug Information Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body. Source: AHFS Consumer Medication Information
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Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C. Preventive action of vitamin C on nitrosamine formation. Prolongation of survival times of terminal cancer patients by administration of large dose... Vitamin C and cancer: an overview. The influence of ascorbic acid on the growth of solid tumors in mice and on tumor control ...
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All Databases
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PubMed
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Protein
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Journals
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for Details
Note: Performing your original search, Inhibition of Benzo(a)pyrene Carcinogenesis in Rats with Vitamin C, in PubMed will retrieve 3 records.
Display All: 1
AbstractPlus
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20
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Review: 0 Links
1: J Cancer Res Clin Oncol. 1980;97(1):91-6.
Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C.
Related Articles Inhibition of benzo(a)pyrene-induced carcinogenesis by vitamin C alone and by vitamin C/vitamin E and selenium/glutathione. [Biol Tr ace El em Res. 2003]
Kallistratos G, Fasske E. The s.c. infection of 10 mg benzo(a)pyrene dissolved in 1 ml tricaprylin induced in Wistar rats local malignant tumors, such as fibrosarcoma, rhabdomyosarcoma, and polymorph cell sarcoma. The growth of the tumors was relatively rapid, reaching weights of 140-155 g before rats died 142-168 days after the administration of the carcinogen. On the contrary, under the same experimental conditions, high doses of Vitamin C about 525 mg/day/rat administered orally in drinking water (total amount of Vitamin C 55 g/rat corresponding to 40% of their body weight ) inhibited to a great extent the benzo(a)pyrene carcinogenesis. Only one slowly growing rhabdomyosarcoma (13 g of weight) was developed showing characteristic damage of malignant cells and partial replacement of the neoplastic area with granuloma tissue. The significance ov Vitamin C for cancer prevention and treatment is discussed.
The paradoxical effect of vitamin C on benzo[a]pyrene-induced tumors and malignancy. [Natu rwisse nschaften. 1984] Dose-dependent effect of trichloropropene oxide on benzo[a]pyrene carcinogenesis. [JCancer ResClin Oncol. 1980] Review Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum [I ntannuum JT oxicol.fruit 2007] Review Prolongation of the survival time of tumor bearing Wistar rats through a simultaneous oral administration of vitamins C + E and selenium [ Pro gClinwith Bi ol Res. 1988] » See Reviews...
PMID: 7400211 [PubMed - indexed for MEDLINE]
|
» See All...
Patient Drug Information Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body. Source: AHFS Consumer Medication Information
Recent Activity Turn Off
Clear
Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C. Preventive action of vitamin C on nitrosamine formation. Prolongation of survival times of terminal cancer patients by administration of large dose... Vitamin C and cancer: an overview. The influence of ascorbic acid on the growth of solid tumors in mice and on tumor control ...
Display
AbstractPlus
Show
20
Sort By
Send to
Write to the Help Desk NCBI | NLM | NIH Department of Health & Human Services Privacy Statement | Freedom of Information Act | Disclaimer
