Nitrogenous wastes impairs platelets
Malfunction of RAAS
Decreased Erythropoietin Production
Bleeding tendencies
Na & H2O retention
Continuous decline in renal function
Toxins irritate pericardial sac
> 90 % of kidney damage
Pericarditis
Increased blood pressure
Oliguria Hypertension
Edema
Urea deposits on the skin
Decreased Immune system
Uremic frost
Cardiac Tamponade
ANEMIA Decreased Urine Output
Toxins impair immune system
- Reduction in renal capillaries -Scarring of Glomeruli - Atrophy & Fibrosis of Renal tubules
-fatigue - weakness
Pulmonary Edema, Peripheral Edema
Stage IV END-STAGE RENAL DISEASE (ESRD) GFR <10%
Heart Failure
Continuous Multisystem Affectation Multiple Organ Failure
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DEATH
Risk for superinfection ┼ Sepsis
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Toxins affect CNS
Uremic Encephalopathy -changes in mentation/ psychiatric symptoms -irritability -fatigue -insomnia