Metronidazole Prescription Drug

Metronidazole Prescription Drug

CHEAP Metronidazole .

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The active material: Metronidazole prescription meds - 250 mH. Auxiliary substances: starch is maize, lactose, [polividon], microcrystalline cellulose, stearate of magnesium, talc, [krospovidon], glycerin. Pharmacological properties - Antimicrobial action of the group of nitro -5 imidazoles. Possesses the wide spectrum of action with respect to of anaerobic microorganisms - Peptococcus, Peptostreptococcus, Bacteroides sp., Clostridium sp., Fusobacterium, Prevotella, Veilonella. Suppresses the development of the simple - Trichomonas of vaginalis, Giardia of intestinalis (Lamblia of intestinalis), Entamoeba of hystolytica. Pharmacokinetics - after internal administration Metronidazole rapidly and almost completely is sucked. The consumption of food does not influence the absorption of preparation. The plasma concentrations of

Metronidazole are proportional to the introduced dose. Maximum plasma concentrations 5-10 g/ml note the hour after the introduction of one-time dose 250 and 500 mH. Metronidazole rapidly penetrates the cloth (lungs, kidney, the liver, the skin), the bile, the cerebro-spinal fluid, the saliva, the [vaginapnyy] secret, the seed liquid and the breast milk; it penetrates the placental barrier. The average period of [polueliminatsii] in the healthy persons - 8-10 hours, connection with the proteins of the blood insignificant and do not exceed 810%. Metabolism is achieved in the liver via oxidation and binding with the glucuronic acid. The removal of preparation is achieved to 40-70% through the kidneys (in the fixed shape - of about 20% of the taken dose), also, with the feces. In patients with the hepatic insufficiency the period of half-life remains without the changes. Indications to the application trichomona and urethritis in women, trichomona urethritis in men, lambliasis, amoebic dysentery; the anaerobic infections, caused by sensitive to the preparation microorganisms. Combined therapy of the heavy mixed aerobic- anaerobic infections. Preventive maintenance of anaerobic infection with the surgical interventions (especially on the organs of abdominal cavity, the urinary tracts). Chronic alcoholism. In the combination: chronic gastritis in the phase of aggravation, stomach ulcer and duodenum in the phase of the aggravations, associated from Helicobacter of pylori. Contra-evidence - the increased sensitivity to the preparation or other derivatives of imidazole.