Drug Metronidazole

  • June 2020
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NURS 1566 Clinical Medication Worksheet Generic Name Trade Name Metronidazole Flagyl Peak Onset End of infusion

Classification Dose Route Time/frequency Anti-infective 500 mg IV Q 8 hr Duration Normal Dosage Range

Rapid

6-8 hr

500 mg Q 6-8 hrs, do not exceed 4 g / day

Why is your patient getting this medication: May be used for intra-abdominal infections; perioperative prophylactic agent in colorectal surgery

For IV meds, compatibility with IV drips and /or solutions No incompatibilities noted

Mechanism of action and indications:

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity

Disrupts DNA and protein synthesis in susceptible organisms. Bactericidal

Common side effects: CNS: Seizures, dizziness, H/A GI: abdominal pain, anorexia, N/V, diarrhea Derm: rashes Hemat: leukopenia Neuro: peripheral neuropathy Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically): None noted

Lab value alterations caused by medicine: May alter results of serum AST, ALT, LDH Be sure to teach the patient the following about this medication: May cause dizziness or light headedness, May cause urine to turn dark. Report any S/S of super infections (black furry overgrowth on tongue, loose or foul-smelling stools.

Nursing Process- Assessment (Pre-administration) VS, appearance of urine and stool, and WBC. Monitor neurological status during and after IV infusion. Monitor I/O and weight.

Assessment Why would you hold or not give this med? Signs of super infection and change in neuro signs

Evaluation Check after giving Resolution of S/S of infection

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