Malignant Cells: • In Some Cases Malignant Cells Stand Outlikeaguyina Yellow Dark Suit Playing The Thrombone

MALIGNANT CELLS • In some cases malignant cells stand out like a guy in a yellow dark suit playing the thrombone.

• Adenocarcinoma…tumo r cells form aggregates

• Cell balls

• Papillae

• Gland like groups

• Single file chains

• Lymphoma

• Unusual abnormal bizarre shapes are suggestive of malignancy.

• Cell borders of malignant cells are often sharply defined.

• Malignant nuclear features are the sine qua of a non malignant diagnosis.

• pseudoinclusions

• Large multiple and especially abnormal shaped nucleoli are suspicious for malignancy.

• Mitotic figures are not so helpful in diagnosis unless they are clearly abnormal or numerous.

• In Secretory vacuoles containing epithelial mucin are essentially diagnostic of adenocarcinoma.

• Cytoplasmic lipid can occur in tumors such as renal and hepatocellular carcinoma,cytoplasmic glycogen.

• Keratin formation is diagnostic of squamous cell carcinoma in an effusion.

• Mucinous effusion