List Of Doc

DOC list : www.gamspg.webs.com : © 2009 GAMS Bactericidal for gpc, gpr, gnc & spirochetes Staph aureus HELPS kill enterococci Pseudomonas species, gnr G+c PEcK G+c HEN PEcKS MBC Serious gram neg infections resistant to other beta-lactams, meningitis Serious pseudomonas Serious gonorrhea Gnrs (Klebsiella, pseudomonas, serratia), penicillin allergic pts & those with renal failure who can’t tolerate aminoglycosides Gpc, gnr, anaerobes DOC for enterobacter Serious gram pos multidrugresistant organisms (S aureus, C difficile/PMC) Severe gnr infections, synergistic with β-lactam antibiotics VACUUM Your Bed Room By Friday URTIs, pneumonias, STDs (gpc – Strep infections in pts allergic to penicillin), Mycoplasma, Legionella, Chlamydia, Neisseria Last resort for meningitis (H influenzae, N meningitides, S pneumoniae) Anaerobic infections above diaphragm (B fragilis, C difficile)

Penicillin G (IV), penicillin V (oral) CONDM Ampicillin, amoxicillin Carbenicillin, piperacillin, ticarcillin 1st generation cephalosporins 2nd generation cephalosporins 3rd generation cephalosporins

Ceftazidime Ceftriaxone Aztreonam

Imipenem + cilastin Imipenem + cilastin Vancomycin

Tetracylcines Macrolides

Chloramphenicol

Clindamycin

DOC list : www.gamspg.webs.com : © 2009 GAMS Gram pos & neg, Nocardia, Chlamydia DOC for simple UTI Recurrent UTI, Shigella, Salmonella, PCP Gnr of urinary & GI tracts (incl Pseudomonas), Neisseria, some gram pos Giardia, Entamoeba, Trichomonas, gardnerella vaginalis, anaerobes below diaphragm (Bacteroides, clostridium) H pylori

Sulfonamides Triple sulfas or SMX TMP + sulfonamide Fluoroquinolones

Metronidazole

Metronidazole + bismuth + amoxicillin/tetracycline Resistant gram neg infections Polymyxins M tuberculosis, only one used as solo Isoniazid (INH) prophylaxis against TB M tuberculosis, delays resistance to Rifampin (always used in combination dapsone when used for leprosy with other drugs except in tx of meningococcal carrier state & chemoprophylaxis in contacts of kids with H flu type B) DOC for nonsurgical meningococcal Rifampin prophylaxis Nonsurgical gonorrhea prophylaxis Ceftriaxone Nonsurgical syphilis prophylaxis Benzathine penicillin G Prophylaxis if history of recurrent TMP-SMX UTIs DOC for nonsurgical PCP prophylaxis TMP Systemic mycoses, intrathecally for Amphotericin B fungal meningitis “Swish & swallow” for oral thrush Nystatin Cryptococcal meningitis in AIDS pts Fluconazole & candidal infections of all types

DOC list : www.gamspg.webs.com : © 2009 GAMS Blastomyces, Coccidiodes, Histoplasma, C albicans, hypercortisolism Superficial infections (inhibits growth of dermatophytes (tinea, ringworm) Propylaxis for influenza A, Parkinson’s Dz RSV Influenza A & B HSV, VZV, EBV, mucocut & genital herpes lesions, propylaxis in immunocompromised pts CMV (esp if immunocompromised) CMV retinitis in immunocompromised pts when ganciclovir fails Triple therapy for HIV when CD4<500 or high viral load Mother with HIV, reduces risk of fetal transmission Chronic hepatitis B & C, Kaposi’s sarcoma Onchocerciasis (“river blindness”) Nematode/roundworm (pinworm, whipworm) Giant roundworm (Ascaris), hookworm (Necator/Ancylostoma), pinworm (Enterobius) Trematode/fluke (schistosomes, Paragonimus, Clonorchis), cysticercosis Cestode/tapeworm (D latum, Taenia spp) except cysticercosis

Ketoconazole

Griseofulvin (oral)

Amantadine Ribavirin Zanamivir Acyclovir

Ganciclovir Foscarnet 2 NRTIs with protease inhibitor Zidovudine (AZT) Interferons Ivermectin Mebendazole/thiabendazole Pyrantel pamoate

Praziquantel

Niclosamide

DOC list : www.gamspg.webs.com : © 2009 GAMS Leishmaniasis Malaria Latent hypnozoite (liver) forms of malaria (P vivax & ovale) PCP propylaxis Chagas’ dz, American trypanosomiasis (T cruzi) African trypanosomiasis (sleeping sickness) Postop & neurogenic ileus & urinary retention Glaucoma (cholinomimetic) Postop & neurogenic ileus & urinary retention, myasthenia gravis, reversal NMJ blockade (postop) Myasthenia gravis Dx of myasthenia gravis Glaucoma & atropine OD Regenerates active cholinesterase, tx of organophosphate exposure Dilate pupil, ↓ acid secretion in acidpeptic dz, ↓ urgency in mild cystitis, ↓ GI motility, ↓ airway secretions, tx organophosphate poisoning Parkinson’s Dz (antimuscarinic in CNS) Motion sickness (antimuscarinic in CNS) Mydriasis & cyclopegia (antimuscarinic in eye) Asthma, COPD (antimuscarinic in resp)

Pentavalent antimony Chloroquine, quinine, mefloquine Primaquine Pentamidine Nifurtimox Suramin Bethanechol Carbachol, pilocarpine, echothiophate, physostigmine Neostigmine

Pyridostigmine Edrophonium Physostigmine (crosses BBB) Pralidoxime Atropine

Benztropine Scopolamine Atropine, homatropine, tropicamide Ipratropium

DOC list : www.gamspg.webs.com : © 2009 GAMS Muscle paralysis in surgery/mechanical ventilation (depolarizing) Muscle paralysis in surgery/mechanical ventilation (nondepolarizing) Tx of malign hyperthermia Anaphylaxis, glaucoma (open angle), asthma, hypoTN HypoTN (↓ renal perfusion) AV block (rare) Shock (↑ renal perfusion), heart failure Shock, heart failure Narcolepsy, obesity, attention deficit disorder Nasal congestion, urinary incontinence, hypoTN Pupil dilator, vasoconstriction, nasal decongestion Asthma (β2 selective) Vasoconstriction & local anesthesia HTN (esp with renal dz b/c no ↓ blood flow to kidney) Pheochromocytoma HTN, urinary retention in BPH HTN, angina pectoris, MI, CHF SVT Glaucoma (β blocker) Glaucoma (diuretic) Glaucoma (PG) Sedative for anxiety, seizures

Succinylcholine

Tubocurarine, atracurium, mivacurium, pancuronium, vecuronium Dantrolene Epinephrine Norepinephrine Isoproterenol Dopamine Dobutamine Amphetamine Ephedrine Phenylephrine Albuterol, terbutaline Cocaine Clonidine, α-methyl dopa Phenoxybenzamine, phentolamine Prazosin, terazosin, doxazosin (α1 selective) β blockers Propranolol, esmolol Timolol, betaxolol, carteolol Acetazolamide, dorzolamide Lantanoprost Barbiturates

DOC list : www.gamspg.webs.com : © 2009 GAMS Induction of anesthesia (barbiturate), short surgical procedures Anxiety, spasticity, detoxification (esp alcohol withdrawal – delirium tremens) Status epilepticus (benzodiazepine) Schizophrenia, psychosis (tx for + sx) Schizophrenia (tx for + & - sx) OCD, anxiety disorder, depression Mood stabilizer for bipolar affective disorder, blocks relapse & acute manic events Endogenous depression Bedwetting (TCA) OCD (TCA) Major depressive disorders Smoking cessation Generalized anxiety disorder Atypical depressions (with psychotic/ phobic features), anxiety, hypochondriasis Adjunctive agent to L-dopa in tx of Parkinson’s dz Parkinsonism (dopa agonists) Pain, acute pulm edema

Cough suppression (opioid) Diarrhea (opioid) Maintenance programs for addicts

Thiopental

Benzodiazepines

Diazepam Neuroleptics (Thioridazine, haloperidol, fluphenazine, chlorpromazine) Clozapine, olanzapine, risperidone Olanzapine Lithium

SSRIs, TCAs Imipramine Clomipramine Trazodone, buproprion, venlafaxine, mirtazapine Buproprion Venlafaxine MAOIs

Selegiline (deprenyl) L-dopa/carbidopa, bromocriptine Opioids (Morphine, fentanyl, codeine, heroin, methadone, meperidine, dextromethorphan) Dextromethorphan Loperamide, diphenoxylate Methadone

DOC list : www.gamspg.webs.com : © 2009 GAMS (opioid) Acute migraine, cluster headache attacks Control vomiting postop & in pts undergoing cancer therapy Partial seizures (simple & complex) Generalized tonic-clonic Generalized absence Status epilepticus Trigeminal neuralgia DOC for generalized tonic-clonic Most common drug used for endoscopy, used adjunctively with gaseous anesthetics & narcotics Dissociative anesthetic, CV stimulant, ↑ cerebral blood flow Used with other CNS depressants during general anesthesia (narcotics) Rapid anesthesia induction & short procedures, less post-op nausea than thiopental Minor surgical procedures, spinal anesthesia Severe HTN, CHF HTN, angina, arrhythmias HTN, CHF, diabetic renal dz Glaucoma, urinary alkalinization, metabolic alkalosis, altitude sickness Edematous states (CHR, cirrhosis,

Sumatriptan Ondansetron Phenytoin, carbamazepine, lamotrigine, gabapentin, topiramate Phenytoin, carbamazepine, lamotrigine, gabapentin, Phenobarbital, valproate Ethosuximide, valproate Phenytoin, benzodiazepines (diazepam/lorazepam) Carbamazepine Phenytoin Midazolam

Ketamine Morphine, fentanyl

Propofol

Procaine, cocaine, tetracaine, lidocaine, bupivacaine Hydralazine Ca2+ channel blockers ACE inhibitors, losartan Acetazolamide Furosemide

DOC list : www.gamspg.webs.com : © 2009 GAMS nephritic syndrome, pulm edema), HTN, hypercalcemia Diuresis in pts allergic to sulfa drugs HTN, CHF, Ca2+ stone formation, nephrogenic diabetes insipidus Hyperaldosteronism, K+ depletion, CHF Shock, drug OD, ↓ intracranial/intraocular pressure Angina, pulm edema, aphrodisiac, erection-enhancer CHF, atrial fibrillation Digoxin/digitalis OD Atrial & ventricular arrhythmias Acute ventricular arrhythmias (esp post MI), digitalis-induced arrhythmias V-tachs that progress to V-fib, intractable SVT (last resort in refractory tachyarrhyth-mias) Used when other antiarrhythmics fail Prevention of nodal arrhythmias (eg SVT) DOC in diagnosing/abolishing AV nodal arrhythmias Depresses ectopic pacemakers (esp in digoxin toxicity) Effective in torsades de pointes & digoxin toxicity Leukemias, lymphomas, chorioca,

Ethacrynic acid Hydrochlorothiazide Spironolactone, Triamterene, Amiloride Mannitol Nitroglycerin, isosorbide dinitrate Cardiac glycosides (digoxin) Slowly normalize K+, lidocaine, cardiac pacer, anti-dig Fab fragments, Mg2+ Class IA (Na+ channel blockers) Class IB (Na+ channel blockers)

Class IC (Na+ channel blockers)

Class III (K+ channel blockers) Class IV (Ca2+ channel blockers) Adenosine K+ Mg+ Methotrexate

DOC list : www.gamspg.webs.com : © 2009 GAMS sarcomas, abortion, ectopic pregnancy, RA, psoriasis Colon cancer & other solid tumors, BCC (topical), synergy with methotrexate Leukemias, lymphomas (not CLL/Hodgkin’s) CML Non-Hodgkin’s lymphoma, breast & ovarian ca, an immunosuppressant Brain tumors (incl glioblastoma multiforme) Testicular, bladder, ovary, lung ca Part of ABVD combo regimen for Hodgkin’s & for myelomas, sarcomas, & solid tumors (breast, ovary, lung) Testicular cancer, lymphomas Oat cell ca of lung & prostate, testicular ca Most commonly used glucocorticoid in cancer chemo, used in CLL, Hodgkin’s lymphoma (in MOPP regimen), an immunosuppressant used in autoimmune dz) Breast cancer Part of MOPP regimen for lymphoma, Wilms’ tumor, chorioca Ovarian & breast ca Acetaminophen OD Salicylate OD Anticholinesterase/organophosphate OD Antimuscarinic/anticholinergic OD

5-FU

6-MP Busulfan Cyclophosphamide Nitrosureas Cisplatin Doxorubicin (Adriamycin)

Bleomycin Etoposide Prednisone

Tamoxifen, raloxifene Vincristine (Oncovorin), vinblastine Paclitaxel N-acetylcysteine Alkalinize urine, dialysis Atropine, pralidoxime Physostigmine salicylate

DOC list : www.gamspg.webs.com : © 2009 GAMS β blocker OD Iron poisoning Lead poisoning Arsenic, mercury, or gold poisoning Copper, arsenic, or gold poisoning CN poisoning Methemoglobin problem CO poisoning Methanol, ethylene glycol (antifreeze) poisoning Opioid OD Benzodiazepine OD TCA OD Heparin OD Warfarin OD t-PA, streptokinase OD Erectile dysfunction Infertility Abortifacient Peptic ulcers, gastritis, esophageal reflux, Zollinger-Ellison syndrome Peptic ulcer dz Prevention of NSAID-induced peptic ulcers, maintains PDA Immediate anticoagulation for PE, stroke, angina, MI, DVT, can use during pregnancy Chronic anticoagulation, can’t use during pregnancy Early MI Decreases incidence/recurrence of

Glucagon Deferoxamine CaEDTA, dimercaprol, succimer, penicillamine Dimercaprol (BAL), succimer Penicillamine Nitrite, hydroxocobalamine, thiosulfate Methylene blue 100% O2, hyperbaric O2 Ethanol, dialysis, fomepizole Naloxone/naltrexone Flumazenil NaHCO3 (nonspecific) Protamine sulfate Vit K, fresh frozen plasma Aminocaproic acid Sildenafil Clomifene Mifepristone (RU-486) H2 blockers, omeprazole, lansoprazole Sucralfate Misoprostol Heparin

Warfarin (Coumadin) Thrombolytics (Streptokinase, urokinase, tPA, APSAC) Ticlopidine, clopidogrel

DOC list : www.gamspg.webs.com : © 2009 GAMS thrombotic stroke, acute coronary syndrome, coronary stenting Antipyretic, analgesic, antiinflammatory, antiplatelet To close a patent ductus arteriosus Rheumatoid & osteoarthritis Antipyretic, analgesic, lacks antiinflammatory properties Addison’s dz, inflammation, immune suppression, asthma Prophylaxis of asthma, not effective during active asthmatic attack Long-acting agent for prophylaxis of asthma 1st line therapy for chronic asthma Acute gout Chronic gout Life-threatening hyperkalemia, stress-induced hyperglycemia Oral hypoglycemic used to stim release of endogenous insulin in NIDDM, inactive in IDDM Oral hypoglycemic, can be used in pts w/o islet function Monotherapy in Type II DM or in combination with other hypoglycemics Infertility (pulsatile), prostate cancer (continuous: use with flutamide), uterine fibroids Hyperthyroidism

Aspirin & other NSAIDs Indomethacin COX II inhibitors (Celecoxib, rofecoxib) Acetaminophen Glucocorticoids Cromolyn Salmeterol Corticosteroids Indomethacin (more common), colchicine Probenecid, allopurinol Insulin Sulfonylureas (Tolbutamide, chlorpropamide, glyburide, glipizide) Metformin “Glitazones”, α-glucosidase inhibitors (acarbose, miglitol) Leuprolide

Propylthiouracil

DOC list : www.gamspg.webs.com : © 2009 GAMS BPH Prostate ca Tx of polycystic ovarian syndrome to prevent hirsutism Suppresses organ rejection after transplantation, selected autoimmune disorders Kidney transplantation, autoimmune disorders (incl glomerulonephritis & hemolytic anemia) Potent immunosuppressive used in organ transplant recipients DOC for chronic tx of simply hypothyroidism (myxedema) Thyroid storm Tx of angina that consistently decreases the heart rate & can prevent vasospastic angina attacks Chemoprophylaxis for chloroquineresistant P falciparum endemic regions Microcytic anemia of pregnancy DOC for acute attacks of nonfalciparum malaria

Finasteride Flutamide Ketoconazole, spironolactone Cyclosporine

Azathioprine

Tacrolimus (FK506) Levothyroxine (T4) Propylthiouracil Verapamil

Mefloquine

Ferrous sulfate Chloroquine

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DOC list : www.gamspg.webs.com : © 2009 GAMS

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DOC list : www.gamspg.webs.com : © 2009 GAMS