Khaled Alshorafa Ib Vaccination Prorame L

Infectious Bronchitis vaccination program ((IB IB( it is an important disease in poultry production . it cause large( economic losses in Broilers , Layers and breeders .these disease affect . respiratory system , kidneys, and oviduct

Aim of vaccination against Infectious Bronchitis It is important to establish the purpose of vaccination.

Broilers - Vaccination is focused on reducing the economic losses caused by IB infections as these are reflected in weight loss and general poor performance of the flock.

Layers and breeders - The aim of vaccination is to protect the oviduct as IB infections may result in false layers, drops in production and changes in the internal and external quality of the eggs. In this context vaccination of young chickens is often done at an early age (first day(s( of life(, and especially in broilers focusing on inducing enough protection so as to cover the whole fattening period. In layers and breeders the programs are focused in protecting the oviduct during the first weeks of life with modified live vaccines. Later on during the production period immunity needs to be broad and long lasting, and inactivated vaccines are often used.

: Etiologic agent the Disease caused by virus belong to cornavirus super family, (IB( virus is :antigenically distinct from other coronaviruses , the virus had eight classical types .Massachusetts 41 -1 .(Connecticute(Florida,Clark333,Arkansas 99 -2 .Georgea -3 .Delware -4 .Iowa 97 -5 .Iowa 609 -6 .New Hampshire -7 .(Australian(T-strain -8 These serotypes participate in one specific antigen which we can detect by using; agar gel precipitation (AGP)test, serum neutralizing .(test(SN),and (ALLISA

Every type of these types give Homologus Protection , if there infection or vaccination for one type it give complete immunity for the same type only, and if there an infection or vaccination of .one type these don’t give complete immunity for other types

Vaccines: No general vaccination rule can be applied. Each vaccination program must be adapted to the demands of the field situation.Some considerations have to be taken into account when applying IB vaccines: • • • •

At what age protection against Infectious Bronchitis (IB( is most needed. The field viruses present will determine which vaccines (protectotype( to choose. Interference with other (live( vaccinations must be avoided (IB vaccine viruses can interfere with for example Newcastle disease vaccine viruses(. Geographic area .

Used Vaccines: First: live vaccines; it given in drinking water, aerosol , drops in nostril or eye. The live vaccine include the following: (H120) attenuated Massachusetts by using emroynated eggs 120 time, the (H120) vaccine give good immunity but to short time :and so we revaccinate with other dose after 6-8 weeks from the first dose these dose we use (H52( Massachusetts using with emroynated eggs 52 time, so (H52( more virulence than the (H120(, (H52( use only in the second dose after using (H120( in the first dose. Other type of live vaccine Connecticut3 serotype ;it attenuated serotype has the same effect like (H120), but Connecticut3 don’t give wide range of protection like Massachusetts serotypes witch .give wide range of protection for other (IB) virus strains