Facts about IBS Michael Schultz Dunedin Public Hospital
Red Flag Symptoms! Alarm features: Age > 50 Short history of symptoms Weight loss Nocturnal symptoms! Male FHx of CRC Anaemia PR bleeding Recent antibiotic use
Rome III (2006) Recurrent abdo pain/discomfort 3 days per month for the previous 3 months Plus two or more symptoms: Improvement with defaecation Associated with change in frequency Associated with change in stool form Supporting symptoms: • Straining/urgency • Mucus • Bloating/distention
Diagnostic Algorithm DD: Microscopic colitis Coeliac disease Giardia Lactose intolerance Bacterial overgrowth Bile malabsorption CRC
Clinical History
Suspected IBS predominant symptom
diarrhea
pain
constipation
1st level: FBC, coeliac antibodies (0-3%), HADS questionnaire ESR/CRP, stool cultures
Amylase, faecal elastase, CT, U/S
2nd level: colonoscopy, gastroscopy, faecal calprotectin
GP
Specialist
GUT 2007
Treatment Algorithm IBS predominant symptom
diarrhea • • • • •
pain
Cognitive behavioral therapy Psychological treatment Hypnotherapy Dietary challenges – fibers or not? Probiotics 5-HT3 agonists
5-HT3 antagonists • antispasmodics •trycyclic antidepressiva
constipation