Hallmark Findings

  • May 2020
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Hallmark Findings Albumino-Cytologic Dissociation Antiplatelet Antibodies Arachnodactyly Aschoff Bodies Auer Rods Autosplenectomy Babinski Basophilic Stippling of RBCs Bence Jones Protein

Birbeck Granules Blue Bloater Boot-Shaped Heart Bouchard’s Nodes Boutonniere’s Deformity Brown Tumor Brushfield Spots Call-Exner Bodies Cardiomegaly with Apical Atrophy Chancre Chancroid Charcot Triad Charcot-Leyden Crystals Cheyne-Stokes Breathing Chocolate Cysts Chvostek’s Sign Clue Cells Codman’s Triangle Cold Agglutinins Condyloma Lata Cotton Wool Spots Councilman Bodies Crescents In Bowman’s Capsule Currant-Jelly Sputum Curschmann’s Spirals Depigmentation Of Substantia Nigra Donovan Bodies Eburnation Ectopia Lentis Erythema Chronicum Migrans Fatty Liver Ferruginous Bodies Ghon Focus / Complex Gower’s Maneuver Heberden’s Nodes Heinz Bodies

Guillain-Barre (markedly increased protein in CSF with only modest increase in cell count) • idiopathic thrombocytopenic purpura • Marfan’s • rheumatic fever • acute promyelocytic leukemia (AML type M3) • sickle cell anemia • UMN lesion • lead poisoning • multiple myeloma free light chains (either kappa or lambda) •

• • • • • • • • • •

Waldenstrom’s macroglobinemia histiocytosis X (eosinophilic granuloma) Chronic Bronchitis Tetralogy of Fallot osteoarthritis (PIP) rheumatoid arthritis hyperparathyroidism Down’s granulosa cell tumor Chagas’ Disease

1 ° Syphilis Haemophilus ducreyi multiple sclerosis (nystagmus, intention tremor, scanning speech) bronchial asthma cerebral lesion endometriosis Hypocalcemia facial spasm in tetany Gardnerella vaginitis osteosarcoma Mycoplasma pneumoniae • infectious mononucleosis • 2 ° Syphilis • • • • • • • • • •

• • •

HTN dying hepatocytes rapidly progressive (crescentic glomerulonephritis)

• Klebsiella • bronchial asthma • Parkinson’s • • • •

granuloma inguinale (STD) osteoarthritis (polished, ivory-like appearance of bone) Marfan’s Lyme Disease

• • • • • •

Alcoholism asbestosis Tuberculosis (1 ° & 2 ° , respectively) Duchenne’s MD use of arms to stand Osteoarthritis (DIP) G6PDH Deficiency

Hemorrhagic Urticaria Heterophil Antibodies

• •

Henoch-Schonlein infectious mononucleosis (EBV)

• • •

Alzheimer’s Megaloblastic anemia iron-deficiency anemia

lid windowtext .75pt; msoborder-top-alt:solid windowtext .75pt;msoborder-left-alt:solid windowtext .75pt; padding:0in 5.4pt 0in 5.4pt"> infectious mononucleosis (EBV) Hirano Bodies Hypersegmented PMNs Hypochromic Microcytic RBCs Jarisch-Herxheimer Reaction Joint Mice Kaussmaul Breathing Keratin Pearls Keyser-Fleischer Ring Kimmelstiel-Wilson Nodules Koilocytes Koplik Spots Lewy Bodies •

Lines of Zahn Lisch Nodules Lumpy-Bumpy IF Glomeruli McBurney’s Sign Michealis-Gutmann Bodies Monoclonal Antibody Spike Myxedema Negri Bodies Neuritic Plaques Neurofibrillary Tangles Non-pitting Edema Notching of Ribs Nutmeg Liver Painless Jaundice Pannus Pautrier’s Microabscesses Philadelphia Chromosome Pick Bodies Pink Puffer Podagra Port-Wine Stain Posterior Anterior Drawer Sign

• Syphilis over-aggressive treatment of an asymptomatic pt. that causes symptoms 2° to rapid lysis • osteoarthritis (fractured osteophytes) • acidosis • SCCA • Wilson’s • diabetic nephropathy • HPV • measles • Parkinson’s (eosinophilic inclusions in damaged substantia nigra cells) • arterial thrombus • neurofibromatosis (von Recklinhausen’s disease) • poststreptococcal glomerulonephritis • appendicitis (McBurney’s Point is 2/3 of the way from the umbilicus to anterior superior iliac spine) • Malakoplakia • multiple myeloma this is called the M protein (usually IgG or IgA) • MGUS • hypothyroidism • rabies • Alzheimer’s • Alzheimer’s • Myxedema • Anthrax Toxin • Coarctation of Aorta • CHF • pancreatic CA (head) • rheumatoid arthritis • mycosis fungoides (cutaneous T-cell lymphoma) • CML • ALL • Pick’s Disease • Emphysema Centroacinar – smoking Panacinar - α1-antitrypsin deficiency • gout (MP joint of hallux) • Hemangioma

Hemangioma

Posterior Anterior Drawer Sign Psammoma Bodies

tearing of the ACL



Papillary adenocarcinoma of the thyroid Serous papillary cystadenocarcinoma of the ovary Meningioma Mesothelioma • Duchenne muscular dystrophy • multiple myeloma • 2° Syphilis • RMSF • paroxysmal nocturnal hemoglobinuria • Hodgkin’s Disease • chronic bronchitis • Leydig cell tumor • multiple myeloma RBC’s stacked as poker chips • L→R Shunt (VSD, PDA) • Mitral Regurg • LV Failure • Pulmonary Stenosis • Pulmonary HTN • Neisseria meningitidis impressive rash with bugs • Down’s • SLE (also anti-dsDNA) • giant cell tumor of bone • membranous glomerulonephritis • Crohn’s bowel wall thickening • Thalassemia • Familial Hypercholesterolemia • chronic pyelonephritis • gout • membranoproliferative glomerulonephritis • visceral ca, classically pancreatic (migratory thrombophlebitis) • hypocalcemia (carpal spasm) •

• • •

Pseudohypertrophy Punched-Out Bone Lesions Rash on Palms & Soles Red Morning Urine Reed-Sternberg Cells Reid Index Increased Reinke Crystals Rouleaux Formation S3 Heart Sound

S4 Heart Sound Schwartzman Reaction Simian Crease Smith Antigen Soap Bubble on X-Ray Spike & Dome Glomeruli String Sign on X-ray Target Cells Tendinous Xanthomas Thyroidization of Kidney Tophi Tram-Track Glomeruli Trousseau’s Sign

Virchow’s Node Warthin-Finkeldey Giant Cells WBC Casts Wire Loop Glomeruli AFP in amniotic fluid or mother’s serum Uric Acid

↓ FEV1/FVC

These are two entirely different disease processes and different signs, but they unfortunately have the same name. • supraclavicular node enlargement by metastatic carcinoma of the stomach • Measles pyelonephritis lupus nephropathy, type IV Spina Bifida • Anencephaly • Gout • Lesch Nyhan • Myeloproliferative Disorders • Diuretics (Loop & Thiazides) • COPD • • •

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