Flagyl
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NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms) Generic Name Trade Name Metronidazole Flagyl Peak Onset End of infusion Rapid
Classification Anti-infective
Dose 500 mg
Duration 6-8 hours
Why is your patient getting this medication Treatment of abdominal abscess that resulted from surgery one month ago for diverticulitis.
Mechanism of action and indications (Why med ordered) Disrupts DNA and protein synthesis in susceptible organisms.
Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Cimetidine may decrease the metabolism of metronidazole.
Route IVPB
Time/frequency Q 8 hr
Normal dosage range Initial dose 12 mg/kg, then 7.5 mg/kg q 6-8 hr or 500 mg q 6-8 hr (not to exceed 4g/day) RATE OF ADMINISTRATION: Infuse over 60 min Q 8 hr. For IV meds, compatibility with IV drips and/or solutions Flagyl IV TRU is prediluted and ready to use. Prefilled plastic minibags should not be used in series connections; air embolism may result. Crystals may form during refrigeration but will dissolve when warmed to room temp. Preparation of Flagyl IV, powder for reconstitution requires a specific process. Do not use aluminum needles or hubs; color will turn orange/rust. Add 4.4 ml of sterile or bacteriostatic sterile water, or 0.9% or bacteriostatic 0.9% NaCl for injection (100 mg/ml). Dilute further to at least 8 mg/ml with 0.9% NaCl, D5W, or LR. Neutralize solution with 5 mEq sodium bicarbonate for each 500 mg. Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity. Hypersensitivity to parabens (topical only) Common side effects CNS: seizures, dizziness, headache. EENT: tearing (topical only).GI: abdominal pain, anorexia, nausea, diarrhea, dry mouth, furry tongue, vomiting. DERM: rashes. LOCAL: phlebitis at IV site. NEURO: peripheral neuropathy. MISC: superinfection. Lab value alterations caused by medicine May alter results of serum AST, ALT, and LDH tests. Be sure to teach the patient the following about this medication Do not drink alcohol for at least 1 day following treatment. May cause dizziness, lightheadedness.
Nursing Process- Assessment (Pre-administration assessment) Assess for infection (vital signs, appearance of wound, sputum, urine, and stool; WBC) at beginning and throughout therapy.
Assessment Why would you hold or not give this med? Culture and sensitivity results indicate this anti-infective would not be effective against this type of infection.
Evaluation Check after giving Resolution of signs and symptoms of infection. Significant results should be seen within 3 weeks.
Classification Anti-infective
Dose 500 mg
Duration 6-8 hours
Why is your patient getting this medication Treatment of abdominal abscess that resulted from surgery one month ago for diverticulitis.
Mechanism of action and indications (Why med ordered) Disrupts DNA and protein synthesis in susceptible organisms.
Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Cimetidine may decrease the metabolism of metronidazole.
Route IVPB
Time/frequency Q 8 hr
Normal dosage range Initial dose 12 mg/kg, then 7.5 mg/kg q 6-8 hr or 500 mg q 6-8 hr (not to exceed 4g/day) RATE OF ADMINISTRATION: Infuse over 60 min Q 8 hr. For IV meds, compatibility with IV drips and/or solutions Flagyl IV TRU is prediluted and ready to use. Prefilled plastic minibags should not be used in series connections; air embolism may result. Crystals may form during refrigeration but will dissolve when warmed to room temp. Preparation of Flagyl IV, powder for reconstitution requires a specific process. Do not use aluminum needles or hubs; color will turn orange/rust. Add 4.4 ml of sterile or bacteriostatic sterile water, or 0.9% or bacteriostatic 0.9% NaCl for injection (100 mg/ml). Dilute further to at least 8 mg/ml with 0.9% NaCl, D5W, or LR. Neutralize solution with 5 mEq sodium bicarbonate for each 500 mg. Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity. Hypersensitivity to parabens (topical only) Common side effects CNS: seizures, dizziness, headache. EENT: tearing (topical only).GI: abdominal pain, anorexia, nausea, diarrhea, dry mouth, furry tongue, vomiting. DERM: rashes. LOCAL: phlebitis at IV site. NEURO: peripheral neuropathy. MISC: superinfection. Lab value alterations caused by medicine May alter results of serum AST, ALT, and LDH tests. Be sure to teach the patient the following about this medication Do not drink alcohol for at least 1 day following treatment. May cause dizziness, lightheadedness.
Nursing Process- Assessment (Pre-administration assessment) Assess for infection (vital signs, appearance of wound, sputum, urine, and stool; WBC) at beginning and throughout therapy.
Assessment Why would you hold or not give this med? Culture and sensitivity results indicate this anti-infective would not be effective against this type of infection.
Evaluation Check after giving Resolution of signs and symptoms of infection. Significant results should be seen within 3 weeks.
