Farkin Aminoglikosida.doc
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Parameter
Streptomis
Amikasin
Gentamisi
Kanamisin
Tobamisin
Absorpsi
in Buruk
Buruk
n -
-
Buruk
oral Volume
-
-
0,2-
-
0,2-0,3
distribusi T max
1 jam
45-120
0,3L/kg 30-90
-
L/kg 30-60
Binding
34%
menit 0-11 %
menit <30%
-
menit <30%
protein T1/2
2 jam
2-3 jam
2 jam
2-3 jam
2-3,5 jam
eliminasi Eksresi
90%
94-98%
-
-
-
<1%
-
-
-
-
tidak berubah pada urin Ekskresi pada feses Perbandingan farmakokinetik obat segolongan - aminoglikosida
Streptomis
Amikasin
Gentamisi
Kanamisin
Tobamisin
Absorpsi
in Buruk
Buruk
n -
-
Buruk
oral Volume
-
-
0,2-
-
0,2-0,3
distribusi T max
1 jam
45-120
0,3L/kg 30-90
-
L/kg 30-60
Binding
34%
menit 0-11 %
menit <30%
-
menit <30%
protein T1/2
2 jam
2-3 jam
2 jam
2-3 jam
2-3,5 jam
eliminasi Eksresi
90%
94-98%
-
-
-
<1%
-
-
-
-
tidak berubah pada urin Ekskresi pada feses Perbandingan farmakokinetik obat segolongan - aminoglikosida
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