Drugsandtheirantidotes 141225062615 Conversion Gate01

Drugs and their Antidotes The need of antidotes for different drugs happened due to the toxicology of drugs or we may say that due to the misuse of drugs.

Toxicology: The study of the effect of poisons on the function of living systems "All things are poison and nothing is without poison, only the dose permits something not to be poisonous." Paracelsus (1493-1541) ‘Grandfather of Toxicology’ Therapeutic effect

Increasing Dose

Toxic effect

List of common drugs and their Antidotes Name of Drug

Antidote

1. Acetaminophen 2. Curare 3. coumadin 4. Digitalis 5. Cyanide poisoning 6. Benzodiazepine 7. Iron 8. Lead 9. Ethylene poisoning 10. Magnesium sulphate 11. Penicillin 12. Morphine sulphate 13. Vincristine 14. Neostigmine 15. Mestinon 16. Ethylene glycol 17. Caffeine 18. Beta blockers 19. Barbiturates 20. Meyaproterenol 21. Cholinesterase inhibitors 22. Heparine 23. Isoniazid 24. Iron salts

Acetylcycteine Tensilon Vita K Digibind Methylene blue Flumazenil Desferal EDTA , BAL Antizol Calcium gluconate Epinephrine Naloxone hydrochloride Hyaluronidase Pralidoxime chloride Atropine sulfate Ethanol Esmolol Glucagon Charcoal Esnolol Atropine Protamine sulfate Vita b6 Deferoxamine

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25. Warfarin 26. Salicylates 27. Quinidine 28. Muscarinic receptor blockers 29. Calcium channel blockers 30. Cyclophosphamide 31. Dopamine 32. Fluorouracil 33. Insuline inj 34. Methotrexate 35. Tricyclic antidepressants 36. Potassium 37. Chloroqunine 38. Amphetamine 39. Arsenic 40. Carbamate 41. MAOI

Vita K Charcoal Sodium bicarbonate Physostigmine Glucagon MESNA Phentolamie Leucoverin calcium Glucose Leucovorine calcium Phyostigmine Insuline and glucose Diazepam Propranolol Dimercaprol Atropine Phentolamine

References    

The antidote inside the world of new pharma by Barry Werth (2014) Text book of pharmacology by Lipponcott Antidotes Principles and Clinical Applications by Robert Flanagan (2003) Medical toxicology by Richerd C. Dart (2004)

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