Cv-dr. Abdul Hameed
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CURRICULUM VITAE AND PUBLICATIONS OF DR. ABDUL HAMEED PRINCIPAL SCIENTIFIC OFFICER INSTITUTE OF BIOMEDICAL & GENETIC ENGINEERING (IBGE) G. P. O. BOX 2891 ISLAMABAD 44000 PAKISTAN
1
Curriculum Vitae Dr. Abdul Hameed Date of Birth:
July 1, 1966
Office Address:
Principal Scientific Officer Institute of Biomedical and Genetic Engineering (IBGE), 3rd Floor, KRL General Hospital, P. O. Box 2891, 24-Mauve Area, G-9/1 Islamabad, Pakistan. Tel: (92-51) 9260639, 9261138, 9261142 Cellular: 923145222061 Fax: (92-51) 9261144 e.mail: [email protected]
Qualifications:
Ph.D. (2008) Department of Biotechnology, Karachi University, Karachi, Pakistan. Thesis Title: Genetics of eye diseases in Pakistan. M.Sc., (1990), Department of Biological Sciences, Quaid-e-Azam University, Islamabad, Pakistan. FIRST DIVISION Biochemistry and Molecular Biology. B.Sc. (1987), Department of Microbiology, Shah Abdul Latif University, Khair Pur Mir’s, Sind, Pakistan. FIRST DIVISION Microbiology, Biochemistry and Botany.
Research Appointments:
Research Fellow for the Post of Scientific Officer:1990-1991 National Institute for Biotechnology and Genetic Engineering, Lahore, Pakistan. Scientific Officer: January 1992 to January 1995, Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan. Senior Scientific Officer: February 1995 to 2005, Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan. Principal Scientific Officer: December 2006 to present, Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan. Research Training Fellow: (1997-2000) Wellcome Trust Collaborative Research Initiative Grant (No. 049571/2/96/2/JMW/LEC). Research Training Fellow: (2001-2004)
2
Wellcome Trust Collaborative Research Initiative Grant (No. 063406/Z/00/Z/HH/KO). Reseaerch Grants:
The Wellcome Trust CRIG grant 1997-2000 The Wellcome Trust CRIG grant 2001-2004
Research Collaborations:
Department of Molecular Genetics Institute of Ophthalmology (Associated with Moorfields Eye Hospital), University College London,11-43 Bath Street, London EC1V 9EL, UK Department of Child Health St. George's Hospital Medical School, Cranmer Terrace, Tooting, London SW17 0RE, UK
Membership:
Human Genome Organization (HUGO), UK.
Conferences Attended:
Pakistan Genetical Society, International Conference on Genetics, November 26-28, 1996, Islamabad, Pakistan. Fourth Shaukat Khanum Memorial Cancer Symposium, February 22-24, 1999, Lahore, Pakistan. First Human Genome Diversity Workshop, Islamabad, Pakistan, October 9-14, 2000. Human Genome Meeting 2002, April 14-17, 2002, Shanghai, China.
Courses Attended:
Laboratory Training Course On Gene Cloning Organized By: Centre For Advanced Molecular Biology, University Of Punjab, Lahore, Pakistan On behalf of: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
Fields of Specialization:
Human Disease Genetics: Mapping of disease gene(s) by genetic linkage analysis and bioinformatics based identification of disease gene(s). Population Genetics: Study genetic predisposition of Pakistani population against infectious and autoimmune disorders. Human DNA Forensic Analysis: Expert in dealing with Rape, Homicide and Parentage testing. Todate, 100s of cases have been successfully analyzed.
3
LIST OF PUBLICATIONS OF Dr. ABDUL HAMEED PRINCIPAL SCIENTIFIC OFFICER INSTITUTE OF BIOMEDICAL & GENETIC ENGINEERING (IBGE) G. P. O. BOX 2891 ISLAMABAD 44000 PAKISTAN
4
INTERNATIONAL PUBLICATIONS 54.
Hameed A, Nasir M, Ajmal M, Latif L. A novel homozygous 62bp insertion in Ecm1 gene causes lipoid proteinosis in a multigenerational Pakistani family. British Society for Human Genetics, British Human Genetics Conference, 13th August-2nd September, 2009.
53.
Hameed A, Nasir M, Ajmal M, Latif L.Novel human pathological mutations. Gene symbol: ECM1. Disease: Lipoid Proteinosis. Hum Genet. 2009 Aug; 126(2):336.
52. Hameed A, Nasir M, Ajmal M, Latif L. A novel homozygous 62bp insertion in Ecm1 gene
causes lipoid proteinosis in a multigenerational Pakistani family. Gene Bank Accession No. GQ404379, 1st September 2009. 51. M. Nasir, A. Latif, M. Ajmal, M. Ismail and A. Hameed. A novel homozygous 62bp
insertion in Ecm1 gene causes lipoid proteinosis in a multigenerational Pakistani family, British J. of Dermatol. 161(3):688-90 Sep. 2009. 50. Ismail. M., Akhtar N., Hameed A., Abid A., and Khaliq. S. Mapping of disease causing
gene(s) for families suffering from hypertrophic cardiomyopathy (HCM). Genetics – Understanding living systems, XX International Congress of Genetics, Berlin, Germany, July 12-17, 2008. 49. Hussain M., Ali-Ul-Qadar S., Hameed A., Aman A., Riaz A., Iqbal S., Anwar A., and
Azhar A., Molecular characterization of amylase producing strain of Bacillus subtilis. GeneBank, Accession No. EU819144. July 16, 2008. 48. Hussain M., Ali-Ul-Qadar S., Hameed A., Aman A., Riaz A., Iqbal S., Anwar A., and
Azhar A., Characterization and phylogeny of commercially important alpha-amylase and protease producing strains of Bacillus subtilis. GeneBank, Accession No. EU819145. July 16, 2008. 47. Hussain M., Ali-Ul-Qadar S.,
Hameed A., and Azhar A., Identification and characterization of newly isolated dextran producing strain of Leuconostic mesenteroides HA-2 by sequencing the gene fragments. GeneBank, Accession No. EU816359. July 14, 2008.
46. Hameed A., Hussain M., and Azhar A. Analysis of CODIS and Y-STR loci in different
Pakistani Ethnic Groups. 19th International Symposium on Human Identification Features Advances and Applications, California, USA, Oct 2, 2008. 45.
Hameed A, Genetics of eye diseases in Pakistan. Department of Biotechnology, University of Karachi, Karachi, Pakistan. Pp 1-159 (2008).
44.
Khaliq S, Abid A, Hameed A, Anwar K, Mohyuddin A, Ismail M, and Mehdi SQ. Gene symbol: AIPL1. Disease: LCA4. Hum Genet. 116 (6): 542 (2005).
43.
Khaliq S., Abid A., Ismail M., Hameed A., Mohyuddin A., Lall P., Aziz A., Anwar K., and Mehdi SQ. Novel association of RP1 gene mutations with autosomal recessive retinitis pigmentosa. J Med Genet. 42(5):436-8 (2005).
5
42.
Mehdi SQ., Anwar K., Abid A., Ismail M., Hameed A., Lall P., Aziz A., and Khaliq S. Novel evidences of RP1 mutations causing autosomal recessive retinitis pigemntosa in consanguineous Pakistani families. American J. Human Genetics. 2003/W (2004).
41.
Khaliq S., Anwar K., Abid A., Ismail M., Hameed A., and Mehdi SQ. Clinical features of a consanguineous Pakistani family with autosomal recessive cone rod dystrophy (CORD8) and refinement of the disease locus (1q23-q24). 1913/F3 American J. Human Genetics. (2004).
40.
Mehdi SQ., Hameed A., Ismail M., Abid A., and Khaliq S. Biotechnology: The discovery of disease causing genes and the treatment of inherited diseases in man. Biotechnology and Genetic Engineering for Development in the Islamic world, Islamic Academy of Sciences Amman, Jordan. Pp 119-139 (2004).
39.
Mansoor A., Mazhar K., Khaliq S., Hameed A., Rehman S., Siddiqi S., Papaioannou M., Cavalli-Sforza LL., Mehdi SQ., and Ayub Q. Investigation of the Greek ancestry of populations from northern Pakistan. Hum. Genet. 114: 484-490 (2004).
38.
Mehdi SQ., Qamar R., Khaliq s., Mansoor A., ayub Q., Hameed A., Mohyuddin a., Ismail M., Karafet T., Hammer MF., Oefner PJ., Dawis RW., Underhill PA., and Cavalli-Sfroza LL. The genetic history of Pakistani ethnic groups in a global context. Natural Product Chemistry at the Turn of the century. Pp 513-520. (2004).
37.
Hameed A., Abid A., Aziz A., Ismail M., Mehdi SQ., and Khaliq S. Evidence of RPGRIP1 Gene mutations associated with recessive cone-rod dystrophy J Med. Genetics 0: 616-619, (2003).
36.
Ayub Q., Mohyuddin A., Khaliq S., Hameed A., Tyler-Smith C., and Mehdi SQ. DHPLC applications: Finding DNA variation on the Y chromosome. Iranian Journal of Biotechnology. 1: 26-30 (2003).
35.
Ayub Q., Mansoor A., Ismail M., Khaliq S., Mohyuddin A., Hameed A., Mazhar K., Rehman S., Siddiqi S., Papaioannou M., Piazza A., Cavalli-Sforza LL., and Mehdi SQ. A reconstruction of the human evolutionary tree using polymorphic autosomal microsatellite. Am. J. Physical Anthropl. (122)259-268 (2003).
34.
Khaliq S., Aiysha A., Hameed A., Anwar K., Mohyuddin A., Azmat Z., Shami SA., Ismail M., and Mehdi SQ. Mutation screening of Pakistani families with congenital eye disorders. Experimental Eye Research, 76(3) 343–348, (2003).
33.
Ayub Q., Mohyuddin A., Khaliq S., Hameed A., and Mehdi SQ. Mutation Detection by DHPLC. Human Genome Diversity in Islamic countries, 7-8 May 2002, Islamic Republic of Iran. Page 21.
32.
Ismail M., Khaliq S., Hameed A., and Mehdi SQ. Studying inherited diseases using bioinformatics. Human Genome Diversity in Islamic countries, 7-8 May 2002, Islamic Republic of Iran. Page 29.
31.
Khaliq S., Abid A., Ismail M., Hameed A., Anwar K., and Mehdi SQ. Genetic studies of Pakistani families suffering from inherited eye disorders. Human Genome Diversity in Islamic countries, 7-8 May 2002, Islamic Republic of Iran. Page 38 (2002).
6
30.
Mehdi SQ., Abid A., Ismail M., Hameed A., Anwar K., and Khaliq S. CRB-1 gene mutations in Pakistani families suffering from retinal disorders. HGM2002, Shanghai, China, 14-17 April 2002, page 164 (2002).
29.
Khaliq S., Hameed A., Abid A., Ismail M., Anwar K., and Mehdi SQ. A novel mutation in the AIPL1 gene associated with Leber congenital amaurosis in a Pakistani family. HGM2002, Shanghai, China, 14-17 April 2002, page 160 (2002).
28.
Hameed A., Khaliq S., Ismail M., Abid A., K. Anwar, SQ. Mehdi. PRPF31 gene mutation in a Pakistani family mapped on Chromosome 19q13.4 (RP11). HGM2002, Shanghai, China, 14-17 April 2002, page 155 (2002).
27.
Khaliq S., Hameed A., Ismail M., Anwar K., and Mehdi SQ. A novel locus for autosomal dominant nuclear cataract mapped to chromosome 2p12 in a Pakistani family. Invest. Ophthalmol. Visual Sci. 43(7): 2083-2087 (2002).
26.
Mehdi SQ., Ayub Q., Qamar R., Mohyuddin A., Mansoor A., Mazhar K., Hameed A., Ismail M., Rehman S., Siddiqi S., Khaliq S., Papaioannou M., Tyler-Smith C., and Cavalli-Sforza LL. Perspectives on human genome diversity within Pakistan using Y chromosomal and autosomal microsatellite markers. In “Biodiversity:Biomolecular Aspects of Biodiversity and Innovative Utilization”. B Sener (ed) Kluwer Academic/Plenum Publishers, New York, pp. (2002).
25.
Khaliq S., Hameed A., Ayub Q., Mazhar K., Mohyuddin A., Mansoor A., and Mehdi SQ. Frequency of CCR5 gene 32-basrpair deletion in Pakistani ethnic groups. Genetic Testing. 6 123-127 (2002).
24.
Khaliq S., Hameed A., Ismail M., Anwar K., and Mehdi SQ. A novel locus for autosomal dominant nuclear cataract mapped to chromosome 2p12 in a Pakistani family. Invest Ophthalmol Vis Sci. 43(7):2083-2087 (2002).
23.
Mehdi S., Ayub Q, Qamar R, Mohyuddin A, Mansoor A, Mazhar K, Hameed A, Ismail M, Rehman S, Siddiqui S, Khaliq S, Papaioannou M, Tyler-Smith C, and Cavalli-Sforza L L. Perspectives on Human Genome Diversity within Pakistan using Y chromosomal and autosomal microsatellite markers. In Biodiversity:Biomolecular Aspects of Biodiversity and Innovative Bilge Sener (ed) Kluwer Academic/Plenum Publishing Corp. New York, pp. 35-47 (2001).
22.
Hameed A., Khaliq S, Ismail M, Anwar K, Bhattacharya SS and Mehdi SQ. A novel locus for autosomal dominant nuclear cataract mapped to chromosome 2p12-2q13 in a Pakistani family. Am J. Human Genetics 69: 1914 (2001)
21.
Khaliq S, Hameed A., Ismail M, Anwar K, Leroy B, Payne AM, Bhattacharya SS, Mehdi SQ. Locus for autosomal recessive nonsyndromic persistent hyperplastic primary vitreous. Invest Ophthalmol Vis Sci. 42(10): 2225-2228 (2001).
20.
Hameed A., Khaliq S, Ismail M, Anwar K, Mehdi SQ, Bessant D, Payne AM, Bhattacharya SS. A new locus for autosomal recessive retinitis pigmentosa (RP29) mapping to chromosome 4q32-q34 in a Pakistani family. Invest. Ophthalmol. Vis. Sci.; 42(7): 1436-1438 (2001).
7
19.
Ismail M, Abid A., Hameed A., Anwar K., Mehdi SQ and Khaliq S. A missense mutation at codon 846 in CRB-1 gene causes RP12 in a Pakistani family. Am. J. Human Genetics 69:2709 (2001).
18.
Khaliq S, Hameed A., M Ismail, SQ Mehdi, Bessant DAR, AM Payne SS Bhattacharya. Novel locus for autosomal recessive cone-rod dystrophy (CORD8) mapping to chromosome 1q12-q24. Investig. Ophthalmol. Vis. Sci. 41 (12): 37093712 (2000).
17.
Payne A, Vithana E, Khaliq S, Hameed A., Dellar J, Abu-Safieh L, Kermani S, Leroy BP, Mehdi SQ, Moore AT, Bird AC, Bhattacharya, SS. RP1 protein truncating mutations predominate at the RP1 adRP locus. Investig. Ophthalmol. Vis. Sci. 41(13): 4069-4073 (2000).
16.
Khaliq S. Hameed A. Mohyuddin, A. Ayub Q., Qamar R., Mazhar K. and Mehdi S. Q. p53 mutations, polymorphisms, and haplotypes in Pakistani ethnic groups and breast cancer patients. Genetic Testing. 4: 23-29 (2000).
15.
Hameed A., Khaliq, S., Ismail, M., Aub Q. and Mehdi S.Q Susceptibility of the Pakistani population to M-tropic strains of the human immunodeficiency virus. International Human Genome Diversity Workshop, 9-12 Oct. 2000, Biomedical and Genetic Engineering Division Islamabad. Pakistan (2000).
14.
Khaliq, S., Hameed A., Ismail, M., Mazhar K., Rehman S. and Mehdi S.Q The discovery of novel genetic loci and gene products for inherited eye diseases in Pakistani families. International Human Genome Diversity Workshop, 9-12 Oct. 2000, Biomedical and Genetic Engineering Division Islamabad. Pakistan (2000).
13.
Hameed A., Khaliq S, Ismail M, Ebenezer N.D. , Jordan T., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. A novel locus for Leber congenital amaurosis (LCA4) with anterior keratoconous mapping to chromosome 17p13. Investig. Ophthal Vision Sci. 41: 629-633 (2000).
12.
Khaliq, S., Hameed A., Ismail, M., Mehdi S.Q., Bessant, D. A. R, Payne, A.M., Bhattacharya, S.S. Refinement of the locus for autosomal recessive retinitis pigmentosa linked to chromosome 6 in a family of Pakistani origin. American J. Human Genetics, 65(4): 1434 (1999).
11.
Hameed A., Khaliq S, Ismail M, Ebenezer N.D., Jordan T., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. A novel locus for Leber congenital amaurosis (LCA4) with anterior keratoconous mapping to chromosome 17p13. Am. J. Human Genetics. 65: 1408(1999)
10.
Payne, A.M., Anwar, K., Khaliq, S., Hameed A., Ismail, M., Bessant, D. A. R, Mehdi S.Q., Bhattacharya, S.S. Localisation of a gene for autosomal recessive cone-rod dystrophy to chromosome 17p12-13. American J. Human Genetics, 65(4): 2490 (1999).
9.
Payne A.M , Khaliq S., Hameed A., Bessant D.A.R., Mehdi S.Q. and Bhattacharya S.S. Localization of a Gene for Autosomal Recessive Cone-Rod Dystrophy to Chromosome 17p12-13.3. Investig. Ophthal. Vision Sci., 40 (4): S603 (3166-B24) 1999.
8
8.
Berry V, Mackay D., Khaliq S., Francis P.J., Hameed A., Anwar K., Mehdi S.Q., Newbold R.J., Ionides A, Shiels A, Moore T. and Bhattacharya S.S.. Connexin 50 mutation in a family with “zonular nuclear” cataract. Human Genetics. 105: 168-170 (1999).
7.
Hameed A., Khaliq, S., Ismail, M., Ebenezer, N.D., Jordan, T., Mehdi, S.Q., Payne, A.M. and Bhattacharya, S.S. A novel locus for Leber congenital amaurosis (LCA4) with anterior keratoconous mapping to chromosome 17p13. . Am. J. Human Genetics. 65(4): 1408 (1999).
6.
Khaliq S., Hameed A., Ismail M., Mehdi S.Q., Bessant D.A.R, Payne A.M. and Bhattacharya S.S. Refinement of the locus for Autosomal Recessive Retinitis Pigmentosa linked to Chromosome 6 in a family of Pakistani Origin. American J. Human Genetics. 65: 571-574 (1999).
5.
Bessant D.A R., Anwar K., Khaliq S., Hameed A., Ismail M., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. Phenotype of autosomal recessive congenital microphthalmia mapping to chromosome 14q32. British J. Ophthalmology. 83: 919-922 (1999).
4.
Bessant, D. A. R., Khaliq, S., Hameed A., Anwar, K., Mehdi S.Q., Mai Al Maghtheh., Payne,A.M. and Bhattacharya, S.S. Severe autosomal dominant retinitis pigmentoa caused by a novel rhodopsin mutation (Ter349Glu). Human Mutation. Vol. 13: 83-87. (1999).
3.
Bessant D. A. R., Khaliq S., Hameed A., Anwar K., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. The First Locus for autosomal recessive congenital microphthalmia maps to chromosome 14q32. Investig. Ophthal. Vision Sci. 39 (4): S511 (2339-B196) (1998).
2.
Bessant, D. A. R., Khaliq, S., Hameed A., Anwar, K., Mehdi S.Q., Payne,A.M. and Bhattacharya, S.S. A locus for autosomal recessive congenital microphthalmia maps to chromosome 14q32. American J. Human Genetics. 62: 1113-1116. (1998).
1.
Mehdi, S. Q., Qamar, R., Khaliq, S., Mohyuddin, A., Mansoor, A., Ismail, M., Hameed A., Ayub, Q., Sun, B., Underhill, P., Cavalli-Sforza, L. L. and Jin, Li. Clinical and evolutionary genetics of Pakistani populations. ICGEB 10th Anniversary Symposium. Molecular Biology and Biotechnology for Development. 25-27 November 1997, ICGEBTrieste, Italy. pp. 61-63 (1997).
9
NATIONAL PUBLICATIONS 19.
M. Ajaml, M. Nasir, A. Latif, M. Ismail, and A. Hameed. A novel mutation in Ecm1 gene causes lipoid proteinosis in a multigenerational Pakistani family. Pakistan Society for Biochemistry and Molecular Biology, 9th Biennial Conference, Advances in Biochemistry and Molecular Biology. December 17-20, 2008, pp85.
18.
Khaliq S., Hameed A., Khaliq, T., Ayub, Q. and Mehdi, S.Q. New p53 mutations in Pakistani breast cancer patients. (Abstract) Fourth Shaukat Khanum Memorial Cancer Symposium , February 22-24, (1999).
17.
Hameed A., Khaliq. S., Mohyuddin A., Mazhar, K., Ismail, M., Ayub, Q., Mehdi, S.Q. Susceptibility of the Pakistani population to M-tropic strain of the human immunodeficiency virus. (Abstract) Fourth Shaukat Khanum Memorial Cancer Symposium , February 22-24, (1999).
16.
Hameed A., Khaliq, S., Khaliq, T., Qamar, R. and Mehdi, S.Q. The Genetics of breast cancer susceptibility in Pakistan. ibid. pp. 68-71. (1997).
15.
Khaliq, S., Hameed A., Mansoor, A., Ayub, Q. and Mehdi, S.Q. Cell proliferation and interferon gamma response in tuberculosis. The Aga Khan University, Karachi. pp. 2023, (1997).
14.
Mirzajani, F., Naqvi, S., Khatoon, S., Channa, S., Dar, A., Afghan, S., Mazhar, K., Khaliq, S., Hameed A., and Zaidi, Z.H. Biochemical and cytotoxic properties of crude venom and its fractions from Pseudocerastes percicus. 5th International Symposium Structure function Relationship, January 6-9, HEJ Research Institute of Chemistry, Karachi, Pakistan. pp. 72. (1997).
13.
Mehdi, S. Q., Ayub, Q., Hameed A., Khaliq, S., Mansoor, A., Mohyuddin, A., Qamar, R., Hammer, M. and Cavalli-Sforza, L. L. Gene Mutations: The clinical and evolutionary history of man. Prof. Khawaja Salahuddin Memorial Lecture. 8th National Chemistry Conference, 2-4 September, 1997, Lahore, Pakistan. pp. 5-6.
12.
Mansoor, A., Qamar, R., Hameed A., Khaliq, S. and Mehdi, S.Q. β-thalassemia mutations in patients and carriers from Pakistan Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. 43. (1996).
11.
Mohyuddin, A., Ismail, M., Hameed A., Qamar, R. and Mehdi, S.Q. A new gene causing non-syndromic deafness in Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 42. (1996).
10.
Hameed A., Khaliq, S., Khaliq, T., Qamar, R. and Mehdi, S.Q. Frequency of p53 gene mutations in primary breast cancer patients in Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 68-71. (1996).
9.
Naim, A.B., Mohyuddin, A., Qamar, R., Khaliq, S., Mansoor, A., Hameed A., Mazhar, K. and Mehdi, S.Q. HLA-allele and haplotype frequencies in Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 13. (1996).
10
8.
Qamar, R., Mansoor, A., Hameed A., Khaliq, S. and Mehdi, S.Q. Y-chromosome polymorphism of different ethnic groups of Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 12. (1996).
7.
Hameed A., Khaliq, S., Qamar, R., Khaliq, T. and Mehdi, S.Q. Mutations in p53 gene in primary breast cancer patients in Pakistan. Chemical Society of Pakistan, 7 th National Chemistry Conference, June 2-4, Quetta. pp. 25. (1996).
6.
Qamar, R., Mansoor, A., Hasnain, S.S., Hameed, A., Talat, A. and Mehdi, S.Q. The spectrum of β-thalassemia mutations in patients and carriers from Punjab and N. W. F. P. Chemical Society of Pakistan, 7th National Chemistry Conference, June 2-4, Quetta. pp. 59. (1996).
5.
Younus, F., Mohyuddin, A., Ismail, M., Qamar, R., Hasnain, S.S., Khaliq, S., Hameed A., Weber, J.L., Mehdi, S.Q. and Gal, A. Autosomal recessive retinitis pigmentosa locus maps proximal to D1S153: mutations in the rhodopsin and peripherin/RDS genes in Pakistani population. Ibid. pp. 52-56. (1995).
4.
Mansoor, A., Qamar, R., Hasnain, S.S., Hameed A., Khaliq, S. and Mehdi, S.Q. Characterization of mutations in the β-globin gene of thalassemia patients and carriers. Ibid. pp. 63-67. (1995).
3.
Khaliq, S., Hameed A., Mansoor, A., Ayub, Q. and Mehdi, S.Q. Immune response of peripheral blood lymphocytes from TB patients. The Aga Khan University, Karachi. pp. 20-23, (1995).
2.
Khaliq, S., Hameed A. and Mehdi, S.Q. Polymorphism of the T-cell receptor (TCR) gene locus: No evidence for linkage with susceptibility to mycobacterial disease in man. Proceeding of Fourth International Symposium- workshop on the Applications of Molecular Biological Research in Agriculture, Health and Environment, CEMB, Lahore, 123-125. (1995).
1.
Khaliq, S. Hameed A., Mansoor, A. and Mehdi, S.Q. Cellular immune response of peripheral blood lymphocytes from TB patients. 1st International. Physiology Conference Lahore. pp. 33, (1993).
11
1
Curriculum Vitae Dr. Abdul Hameed Date of Birth:
July 1, 1966
Office Address:
Principal Scientific Officer Institute of Biomedical and Genetic Engineering (IBGE), 3rd Floor, KRL General Hospital, P. O. Box 2891, 24-Mauve Area, G-9/1 Islamabad, Pakistan. Tel: (92-51) 9260639, 9261138, 9261142 Cellular: 923145222061 Fax: (92-51) 9261144 e.mail: [email protected]
Qualifications:
Ph.D. (2008) Department of Biotechnology, Karachi University, Karachi, Pakistan. Thesis Title: Genetics of eye diseases in Pakistan. M.Sc., (1990), Department of Biological Sciences, Quaid-e-Azam University, Islamabad, Pakistan. FIRST DIVISION Biochemistry and Molecular Biology. B.Sc. (1987), Department of Microbiology, Shah Abdul Latif University, Khair Pur Mir’s, Sind, Pakistan. FIRST DIVISION Microbiology, Biochemistry and Botany.
Research Appointments:
Research Fellow for the Post of Scientific Officer:1990-1991 National Institute for Biotechnology and Genetic Engineering, Lahore, Pakistan. Scientific Officer: January 1992 to January 1995, Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan. Senior Scientific Officer: February 1995 to 2005, Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan. Principal Scientific Officer: December 2006 to present, Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan. Research Training Fellow: (1997-2000) Wellcome Trust Collaborative Research Initiative Grant (No. 049571/2/96/2/JMW/LEC). Research Training Fellow: (2001-2004)
2
Wellcome Trust Collaborative Research Initiative Grant (No. 063406/Z/00/Z/HH/KO). Reseaerch Grants:
The Wellcome Trust CRIG grant 1997-2000 The Wellcome Trust CRIG grant 2001-2004
Research Collaborations:
Department of Molecular Genetics Institute of Ophthalmology (Associated with Moorfields Eye Hospital), University College London,11-43 Bath Street, London EC1V 9EL, UK Department of Child Health St. George's Hospital Medical School, Cranmer Terrace, Tooting, London SW17 0RE, UK
Membership:
Human Genome Organization (HUGO), UK.
Conferences Attended:
Pakistan Genetical Society, International Conference on Genetics, November 26-28, 1996, Islamabad, Pakistan. Fourth Shaukat Khanum Memorial Cancer Symposium, February 22-24, 1999, Lahore, Pakistan. First Human Genome Diversity Workshop, Islamabad, Pakistan, October 9-14, 2000. Human Genome Meeting 2002, April 14-17, 2002, Shanghai, China.
Courses Attended:
Laboratory Training Course On Gene Cloning Organized By: Centre For Advanced Molecular Biology, University Of Punjab, Lahore, Pakistan On behalf of: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
Fields of Specialization:
Human Disease Genetics: Mapping of disease gene(s) by genetic linkage analysis and bioinformatics based identification of disease gene(s). Population Genetics: Study genetic predisposition of Pakistani population against infectious and autoimmune disorders. Human DNA Forensic Analysis: Expert in dealing with Rape, Homicide and Parentage testing. Todate, 100s of cases have been successfully analyzed.
3
LIST OF PUBLICATIONS OF Dr. ABDUL HAMEED PRINCIPAL SCIENTIFIC OFFICER INSTITUTE OF BIOMEDICAL & GENETIC ENGINEERING (IBGE) G. P. O. BOX 2891 ISLAMABAD 44000 PAKISTAN
4
INTERNATIONAL PUBLICATIONS 54.
Hameed A, Nasir M, Ajmal M, Latif L. A novel homozygous 62bp insertion in Ecm1 gene causes lipoid proteinosis in a multigenerational Pakistani family. British Society for Human Genetics, British Human Genetics Conference, 13th August-2nd September, 2009.
53.
Hameed A, Nasir M, Ajmal M, Latif L.Novel human pathological mutations. Gene symbol: ECM1. Disease: Lipoid Proteinosis. Hum Genet. 2009 Aug; 126(2):336.
52. Hameed A, Nasir M, Ajmal M, Latif L. A novel homozygous 62bp insertion in Ecm1 gene
causes lipoid proteinosis in a multigenerational Pakistani family. Gene Bank Accession No. GQ404379, 1st September 2009. 51. M. Nasir, A. Latif, M. Ajmal, M. Ismail and A. Hameed. A novel homozygous 62bp
insertion in Ecm1 gene causes lipoid proteinosis in a multigenerational Pakistani family, British J. of Dermatol. 161(3):688-90 Sep. 2009. 50. Ismail. M., Akhtar N., Hameed A., Abid A., and Khaliq. S. Mapping of disease causing
gene(s) for families suffering from hypertrophic cardiomyopathy (HCM). Genetics – Understanding living systems, XX International Congress of Genetics, Berlin, Germany, July 12-17, 2008. 49. Hussain M., Ali-Ul-Qadar S., Hameed A., Aman A., Riaz A., Iqbal S., Anwar A., and
Azhar A., Molecular characterization of amylase producing strain of Bacillus subtilis. GeneBank, Accession No. EU819144. July 16, 2008. 48. Hussain M., Ali-Ul-Qadar S., Hameed A., Aman A., Riaz A., Iqbal S., Anwar A., and
Azhar A., Characterization and phylogeny of commercially important alpha-amylase and protease producing strains of Bacillus subtilis. GeneBank, Accession No. EU819145. July 16, 2008. 47. Hussain M., Ali-Ul-Qadar S.,
Hameed A., and Azhar A., Identification and characterization of newly isolated dextran producing strain of Leuconostic mesenteroides HA-2 by sequencing the gene fragments. GeneBank, Accession No. EU816359. July 14, 2008.
46. Hameed A., Hussain M., and Azhar A. Analysis of CODIS and Y-STR loci in different
Pakistani Ethnic Groups. 19th International Symposium on Human Identification Features Advances and Applications, California, USA, Oct 2, 2008. 45.
Hameed A, Genetics of eye diseases in Pakistan. Department of Biotechnology, University of Karachi, Karachi, Pakistan. Pp 1-159 (2008).
44.
Khaliq S, Abid A, Hameed A, Anwar K, Mohyuddin A, Ismail M, and Mehdi SQ. Gene symbol: AIPL1. Disease: LCA4. Hum Genet. 116 (6): 542 (2005).
43.
Khaliq S., Abid A., Ismail M., Hameed A., Mohyuddin A., Lall P., Aziz A., Anwar K., and Mehdi SQ. Novel association of RP1 gene mutations with autosomal recessive retinitis pigmentosa. J Med Genet. 42(5):436-8 (2005).
5
42.
Mehdi SQ., Anwar K., Abid A., Ismail M., Hameed A., Lall P., Aziz A., and Khaliq S. Novel evidences of RP1 mutations causing autosomal recessive retinitis pigemntosa in consanguineous Pakistani families. American J. Human Genetics. 2003/W (2004).
41.
Khaliq S., Anwar K., Abid A., Ismail M., Hameed A., and Mehdi SQ. Clinical features of a consanguineous Pakistani family with autosomal recessive cone rod dystrophy (CORD8) and refinement of the disease locus (1q23-q24). 1913/F3 American J. Human Genetics. (2004).
40.
Mehdi SQ., Hameed A., Ismail M., Abid A., and Khaliq S. Biotechnology: The discovery of disease causing genes and the treatment of inherited diseases in man. Biotechnology and Genetic Engineering for Development in the Islamic world, Islamic Academy of Sciences Amman, Jordan. Pp 119-139 (2004).
39.
Mansoor A., Mazhar K., Khaliq S., Hameed A., Rehman S., Siddiqi S., Papaioannou M., Cavalli-Sforza LL., Mehdi SQ., and Ayub Q. Investigation of the Greek ancestry of populations from northern Pakistan. Hum. Genet. 114: 484-490 (2004).
38.
Mehdi SQ., Qamar R., Khaliq s., Mansoor A., ayub Q., Hameed A., Mohyuddin a., Ismail M., Karafet T., Hammer MF., Oefner PJ., Dawis RW., Underhill PA., and Cavalli-Sfroza LL. The genetic history of Pakistani ethnic groups in a global context. Natural Product Chemistry at the Turn of the century. Pp 513-520. (2004).
37.
Hameed A., Abid A., Aziz A., Ismail M., Mehdi SQ., and Khaliq S. Evidence of RPGRIP1 Gene mutations associated with recessive cone-rod dystrophy J Med. Genetics 0: 616-619, (2003).
36.
Ayub Q., Mohyuddin A., Khaliq S., Hameed A., Tyler-Smith C., and Mehdi SQ. DHPLC applications: Finding DNA variation on the Y chromosome. Iranian Journal of Biotechnology. 1: 26-30 (2003).
35.
Ayub Q., Mansoor A., Ismail M., Khaliq S., Mohyuddin A., Hameed A., Mazhar K., Rehman S., Siddiqi S., Papaioannou M., Piazza A., Cavalli-Sforza LL., and Mehdi SQ. A reconstruction of the human evolutionary tree using polymorphic autosomal microsatellite. Am. J. Physical Anthropl. (122)259-268 (2003).
34.
Khaliq S., Aiysha A., Hameed A., Anwar K., Mohyuddin A., Azmat Z., Shami SA., Ismail M., and Mehdi SQ. Mutation screening of Pakistani families with congenital eye disorders. Experimental Eye Research, 76(3) 343–348, (2003).
33.
Ayub Q., Mohyuddin A., Khaliq S., Hameed A., and Mehdi SQ. Mutation Detection by DHPLC. Human Genome Diversity in Islamic countries, 7-8 May 2002, Islamic Republic of Iran. Page 21.
32.
Ismail M., Khaliq S., Hameed A., and Mehdi SQ. Studying inherited diseases using bioinformatics. Human Genome Diversity in Islamic countries, 7-8 May 2002, Islamic Republic of Iran. Page 29.
31.
Khaliq S., Abid A., Ismail M., Hameed A., Anwar K., and Mehdi SQ. Genetic studies of Pakistani families suffering from inherited eye disorders. Human Genome Diversity in Islamic countries, 7-8 May 2002, Islamic Republic of Iran. Page 38 (2002).
6
30.
Mehdi SQ., Abid A., Ismail M., Hameed A., Anwar K., and Khaliq S. CRB-1 gene mutations in Pakistani families suffering from retinal disorders. HGM2002, Shanghai, China, 14-17 April 2002, page 164 (2002).
29.
Khaliq S., Hameed A., Abid A., Ismail M., Anwar K., and Mehdi SQ. A novel mutation in the AIPL1 gene associated with Leber congenital amaurosis in a Pakistani family. HGM2002, Shanghai, China, 14-17 April 2002, page 160 (2002).
28.
Hameed A., Khaliq S., Ismail M., Abid A., K. Anwar, SQ. Mehdi. PRPF31 gene mutation in a Pakistani family mapped on Chromosome 19q13.4 (RP11). HGM2002, Shanghai, China, 14-17 April 2002, page 155 (2002).
27.
Khaliq S., Hameed A., Ismail M., Anwar K., and Mehdi SQ. A novel locus for autosomal dominant nuclear cataract mapped to chromosome 2p12 in a Pakistani family. Invest. Ophthalmol. Visual Sci. 43(7): 2083-2087 (2002).
26.
Mehdi SQ., Ayub Q., Qamar R., Mohyuddin A., Mansoor A., Mazhar K., Hameed A., Ismail M., Rehman S., Siddiqi S., Khaliq S., Papaioannou M., Tyler-Smith C., and Cavalli-Sforza LL. Perspectives on human genome diversity within Pakistan using Y chromosomal and autosomal microsatellite markers. In “Biodiversity:Biomolecular Aspects of Biodiversity and Innovative Utilization”. B Sener (ed) Kluwer Academic/Plenum Publishers, New York, pp. (2002).
25.
Khaliq S., Hameed A., Ayub Q., Mazhar K., Mohyuddin A., Mansoor A., and Mehdi SQ. Frequency of CCR5 gene 32-basrpair deletion in Pakistani ethnic groups. Genetic Testing. 6 123-127 (2002).
24.
Khaliq S., Hameed A., Ismail M., Anwar K., and Mehdi SQ. A novel locus for autosomal dominant nuclear cataract mapped to chromosome 2p12 in a Pakistani family. Invest Ophthalmol Vis Sci. 43(7):2083-2087 (2002).
23.
Mehdi S., Ayub Q, Qamar R, Mohyuddin A, Mansoor A, Mazhar K, Hameed A, Ismail M, Rehman S, Siddiqui S, Khaliq S, Papaioannou M, Tyler-Smith C, and Cavalli-Sforza L L. Perspectives on Human Genome Diversity within Pakistan using Y chromosomal and autosomal microsatellite markers. In Biodiversity:Biomolecular Aspects of Biodiversity and Innovative Bilge Sener (ed) Kluwer Academic/Plenum Publishing Corp. New York, pp. 35-47 (2001).
22.
Hameed A., Khaliq S, Ismail M, Anwar K, Bhattacharya SS and Mehdi SQ. A novel locus for autosomal dominant nuclear cataract mapped to chromosome 2p12-2q13 in a Pakistani family. Am J. Human Genetics 69: 1914 (2001)
21.
Khaliq S, Hameed A., Ismail M, Anwar K, Leroy B, Payne AM, Bhattacharya SS, Mehdi SQ. Locus for autosomal recessive nonsyndromic persistent hyperplastic primary vitreous. Invest Ophthalmol Vis Sci. 42(10): 2225-2228 (2001).
20.
Hameed A., Khaliq S, Ismail M, Anwar K, Mehdi SQ, Bessant D, Payne AM, Bhattacharya SS. A new locus for autosomal recessive retinitis pigmentosa (RP29) mapping to chromosome 4q32-q34 in a Pakistani family. Invest. Ophthalmol. Vis. Sci.; 42(7): 1436-1438 (2001).
7
19.
Ismail M, Abid A., Hameed A., Anwar K., Mehdi SQ and Khaliq S. A missense mutation at codon 846 in CRB-1 gene causes RP12 in a Pakistani family. Am. J. Human Genetics 69:2709 (2001).
18.
Khaliq S, Hameed A., M Ismail, SQ Mehdi, Bessant DAR, AM Payne SS Bhattacharya. Novel locus for autosomal recessive cone-rod dystrophy (CORD8) mapping to chromosome 1q12-q24. Investig. Ophthalmol. Vis. Sci. 41 (12): 37093712 (2000).
17.
Payne A, Vithana E, Khaliq S, Hameed A., Dellar J, Abu-Safieh L, Kermani S, Leroy BP, Mehdi SQ, Moore AT, Bird AC, Bhattacharya, SS. RP1 protein truncating mutations predominate at the RP1 adRP locus. Investig. Ophthalmol. Vis. Sci. 41(13): 4069-4073 (2000).
16.
Khaliq S. Hameed A. Mohyuddin, A. Ayub Q., Qamar R., Mazhar K. and Mehdi S. Q. p53 mutations, polymorphisms, and haplotypes in Pakistani ethnic groups and breast cancer patients. Genetic Testing. 4: 23-29 (2000).
15.
Hameed A., Khaliq, S., Ismail, M., Aub Q. and Mehdi S.Q Susceptibility of the Pakistani population to M-tropic strains of the human immunodeficiency virus. International Human Genome Diversity Workshop, 9-12 Oct. 2000, Biomedical and Genetic Engineering Division Islamabad. Pakistan (2000).
14.
Khaliq, S., Hameed A., Ismail, M., Mazhar K., Rehman S. and Mehdi S.Q The discovery of novel genetic loci and gene products for inherited eye diseases in Pakistani families. International Human Genome Diversity Workshop, 9-12 Oct. 2000, Biomedical and Genetic Engineering Division Islamabad. Pakistan (2000).
13.
Hameed A., Khaliq S, Ismail M, Ebenezer N.D. , Jordan T., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. A novel locus for Leber congenital amaurosis (LCA4) with anterior keratoconous mapping to chromosome 17p13. Investig. Ophthal Vision Sci. 41: 629-633 (2000).
12.
Khaliq, S., Hameed A., Ismail, M., Mehdi S.Q., Bessant, D. A. R, Payne, A.M., Bhattacharya, S.S. Refinement of the locus for autosomal recessive retinitis pigmentosa linked to chromosome 6 in a family of Pakistani origin. American J. Human Genetics, 65(4): 1434 (1999).
11.
Hameed A., Khaliq S, Ismail M, Ebenezer N.D., Jordan T., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. A novel locus for Leber congenital amaurosis (LCA4) with anterior keratoconous mapping to chromosome 17p13. Am. J. Human Genetics. 65: 1408(1999)
10.
Payne, A.M., Anwar, K., Khaliq, S., Hameed A., Ismail, M., Bessant, D. A. R, Mehdi S.Q., Bhattacharya, S.S. Localisation of a gene for autosomal recessive cone-rod dystrophy to chromosome 17p12-13. American J. Human Genetics, 65(4): 2490 (1999).
9.
Payne A.M , Khaliq S., Hameed A., Bessant D.A.R., Mehdi S.Q. and Bhattacharya S.S. Localization of a Gene for Autosomal Recessive Cone-Rod Dystrophy to Chromosome 17p12-13.3. Investig. Ophthal. Vision Sci., 40 (4): S603 (3166-B24) 1999.
8
8.
Berry V, Mackay D., Khaliq S., Francis P.J., Hameed A., Anwar K., Mehdi S.Q., Newbold R.J., Ionides A, Shiels A, Moore T. and Bhattacharya S.S.. Connexin 50 mutation in a family with “zonular nuclear” cataract. Human Genetics. 105: 168-170 (1999).
7.
Hameed A., Khaliq, S., Ismail, M., Ebenezer, N.D., Jordan, T., Mehdi, S.Q., Payne, A.M. and Bhattacharya, S.S. A novel locus for Leber congenital amaurosis (LCA4) with anterior keratoconous mapping to chromosome 17p13. . Am. J. Human Genetics. 65(4): 1408 (1999).
6.
Khaliq S., Hameed A., Ismail M., Mehdi S.Q., Bessant D.A.R, Payne A.M. and Bhattacharya S.S. Refinement of the locus for Autosomal Recessive Retinitis Pigmentosa linked to Chromosome 6 in a family of Pakistani Origin. American J. Human Genetics. 65: 571-574 (1999).
5.
Bessant D.A R., Anwar K., Khaliq S., Hameed A., Ismail M., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. Phenotype of autosomal recessive congenital microphthalmia mapping to chromosome 14q32. British J. Ophthalmology. 83: 919-922 (1999).
4.
Bessant, D. A. R., Khaliq, S., Hameed A., Anwar, K., Mehdi S.Q., Mai Al Maghtheh., Payne,A.M. and Bhattacharya, S.S. Severe autosomal dominant retinitis pigmentoa caused by a novel rhodopsin mutation (Ter349Glu). Human Mutation. Vol. 13: 83-87. (1999).
3.
Bessant D. A. R., Khaliq S., Hameed A., Anwar K., Mehdi S.Q., Payne A.M. and Bhattacharya S.S. The First Locus for autosomal recessive congenital microphthalmia maps to chromosome 14q32. Investig. Ophthal. Vision Sci. 39 (4): S511 (2339-B196) (1998).
2.
Bessant, D. A. R., Khaliq, S., Hameed A., Anwar, K., Mehdi S.Q., Payne,A.M. and Bhattacharya, S.S. A locus for autosomal recessive congenital microphthalmia maps to chromosome 14q32. American J. Human Genetics. 62: 1113-1116. (1998).
1.
Mehdi, S. Q., Qamar, R., Khaliq, S., Mohyuddin, A., Mansoor, A., Ismail, M., Hameed A., Ayub, Q., Sun, B., Underhill, P., Cavalli-Sforza, L. L. and Jin, Li. Clinical and evolutionary genetics of Pakistani populations. ICGEB 10th Anniversary Symposium. Molecular Biology and Biotechnology for Development. 25-27 November 1997, ICGEBTrieste, Italy. pp. 61-63 (1997).
9
NATIONAL PUBLICATIONS 19.
M. Ajaml, M. Nasir, A. Latif, M. Ismail, and A. Hameed. A novel mutation in Ecm1 gene causes lipoid proteinosis in a multigenerational Pakistani family. Pakistan Society for Biochemistry and Molecular Biology, 9th Biennial Conference, Advances in Biochemistry and Molecular Biology. December 17-20, 2008, pp85.
18.
Khaliq S., Hameed A., Khaliq, T., Ayub, Q. and Mehdi, S.Q. New p53 mutations in Pakistani breast cancer patients. (Abstract) Fourth Shaukat Khanum Memorial Cancer Symposium , February 22-24, (1999).
17.
Hameed A., Khaliq. S., Mohyuddin A., Mazhar, K., Ismail, M., Ayub, Q., Mehdi, S.Q. Susceptibility of the Pakistani population to M-tropic strain of the human immunodeficiency virus. (Abstract) Fourth Shaukat Khanum Memorial Cancer Symposium , February 22-24, (1999).
16.
Hameed A., Khaliq, S., Khaliq, T., Qamar, R. and Mehdi, S.Q. The Genetics of breast cancer susceptibility in Pakistan. ibid. pp. 68-71. (1997).
15.
Khaliq, S., Hameed A., Mansoor, A., Ayub, Q. and Mehdi, S.Q. Cell proliferation and interferon gamma response in tuberculosis. The Aga Khan University, Karachi. pp. 2023, (1997).
14.
Mirzajani, F., Naqvi, S., Khatoon, S., Channa, S., Dar, A., Afghan, S., Mazhar, K., Khaliq, S., Hameed A., and Zaidi, Z.H. Biochemical and cytotoxic properties of crude venom and its fractions from Pseudocerastes percicus. 5th International Symposium Structure function Relationship, January 6-9, HEJ Research Institute of Chemistry, Karachi, Pakistan. pp. 72. (1997).
13.
Mehdi, S. Q., Ayub, Q., Hameed A., Khaliq, S., Mansoor, A., Mohyuddin, A., Qamar, R., Hammer, M. and Cavalli-Sforza, L. L. Gene Mutations: The clinical and evolutionary history of man. Prof. Khawaja Salahuddin Memorial Lecture. 8th National Chemistry Conference, 2-4 September, 1997, Lahore, Pakistan. pp. 5-6.
12.
Mansoor, A., Qamar, R., Hameed A., Khaliq, S. and Mehdi, S.Q. β-thalassemia mutations in patients and carriers from Pakistan Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. 43. (1996).
11.
Mohyuddin, A., Ismail, M., Hameed A., Qamar, R. and Mehdi, S.Q. A new gene causing non-syndromic deafness in Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 42. (1996).
10.
Hameed A., Khaliq, S., Khaliq, T., Qamar, R. and Mehdi, S.Q. Frequency of p53 gene mutations in primary breast cancer patients in Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 68-71. (1996).
9.
Naim, A.B., Mohyuddin, A., Qamar, R., Khaliq, S., Mansoor, A., Hameed A., Mazhar, K. and Mehdi, S.Q. HLA-allele and haplotype frequencies in Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 13. (1996).
10
8.
Qamar, R., Mansoor, A., Hameed A., Khaliq, S. and Mehdi, S.Q. Y-chromosome polymorphism of different ethnic groups of Pakistan. Pakistan Genetical Society, International Conference on Genetics, November 26-28, Islamabad. pp. 12. (1996).
7.
Hameed A., Khaliq, S., Qamar, R., Khaliq, T. and Mehdi, S.Q. Mutations in p53 gene in primary breast cancer patients in Pakistan. Chemical Society of Pakistan, 7 th National Chemistry Conference, June 2-4, Quetta. pp. 25. (1996).
6.
Qamar, R., Mansoor, A., Hasnain, S.S., Hameed, A., Talat, A. and Mehdi, S.Q. The spectrum of β-thalassemia mutations in patients and carriers from Punjab and N. W. F. P. Chemical Society of Pakistan, 7th National Chemistry Conference, June 2-4, Quetta. pp. 59. (1996).
5.
Younus, F., Mohyuddin, A., Ismail, M., Qamar, R., Hasnain, S.S., Khaliq, S., Hameed A., Weber, J.L., Mehdi, S.Q. and Gal, A. Autosomal recessive retinitis pigmentosa locus maps proximal to D1S153: mutations in the rhodopsin and peripherin/RDS genes in Pakistani population. Ibid. pp. 52-56. (1995).
4.
Mansoor, A., Qamar, R., Hasnain, S.S., Hameed A., Khaliq, S. and Mehdi, S.Q. Characterization of mutations in the β-globin gene of thalassemia patients and carriers. Ibid. pp. 63-67. (1995).
3.
Khaliq, S., Hameed A., Mansoor, A., Ayub, Q. and Mehdi, S.Q. Immune response of peripheral blood lymphocytes from TB patients. The Aga Khan University, Karachi. pp. 20-23, (1995).
2.
Khaliq, S., Hameed A. and Mehdi, S.Q. Polymorphism of the T-cell receptor (TCR) gene locus: No evidence for linkage with susceptibility to mycobacterial disease in man. Proceeding of Fourth International Symposium- workshop on the Applications of Molecular Biological Research in Agriculture, Health and Environment, CEMB, Lahore, 123-125. (1995).
1.
Khaliq, S. Hameed A., Mansoor, A. and Mehdi, S.Q. Cellular immune response of peripheral blood lymphocytes from TB patients. 1st International. Physiology Conference Lahore. pp. 33, (1993).
11
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