The Cell Cycle Biology 1 CP (Spring ’08)
The Cell Cycle describes the life of a eukaryotic cell they
have a nucleus
Life of a eukaryotic cell is shown in a cycle. Cell Cycle a repeating sequence of cellular growth and division.
Stages of the Cell Cycle Consists of 5 stages Three of the stages together are called Interphase.
These
include G1, , S, & G2
Interphase 1. G1 (First growth phase) Cell
grows rapidly Occupies major portion of the cell’s life
2. S (Synthesis phase) DNA
is copied Each chromosome consists of two chromatids attached at the centromere.
3. G2 (Second Growth Phase) Preparations
are made for the nucleus to
divide. Microtubules are assembled (hollow protein fibers -- move chromosomes during mitosis)
The other 2 phases 4. Mitosis – the process during cell division in which the nucleus of a cell is divided into two nuclei. (Makes an identical copy of another cell) 5. Cytokinesis – “…” in which the cytoplasm divides.
How do cells know when to divide?
Cells have “Checkpoints” “red
light, green light”
1. Cell growth checkpoint (G1): If
conditions are good, moves on to S phase If conditions are not favorable, the cell cycle will stop.
2. DNA Synthesis (G2) checkpoint DNA
replication checked by repair enzymes If passed, the proteins help trigger mitosis.
3. Mitosis checkpoint - If passed, then moves on to G1 phase.