The Respiratory System Dr. Iziddin Fadhil
Copyright 2009, John Wiley & Sons, Inc.
Respiratory System Anatomy
Structurally
Upper respiratory system
Lower respiratory system
Nose, pharynx and associated structures Larynx, trachea, bronchi and lungs
Functionally
Conducting zone – conducts air to lungs
Nose, pharynx, larynx, trachea, bronchi, bronchioles and terminal bronchioles
Respiratory zone – main site of gas exchange
Respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli
Copyright 2009, John Wiley & Sons, Inc.
Structures of the Respiratory System
Copyright 2009, John Wiley & Sons, Inc.
Nose
External nose – portion visible on face Internal nose – large cavity beyond nasal vestibule
Internal nares or choanae Ducts from paranasal sinuses and nasolacrimal ducts open into internal nose Nasal cavity divided by nasal septum Nasal conchae subdivide cavity into meatuses
Increase surface are and prevents dehydration
Olfactory receptors in olfactory epithelium Copyright 2009, John Wiley & Sons, Inc.
Structure of the Nose
Chapter 22, Respiratory System
5
Structure of the Nose
Chapter 22, Respiratory System
Figure 22.2b 6
Copyright 2009, John Wiley & Sons, Inc.
Pharynx
Starts at internal nares and extends to cricoid cartilage of larynx Contraction of skeletal muscles assists in deglutition Functions
Passageway for air and food Resonating chamber Houses tonsils
3 anatomical regions
Nasopharynx Oropharynx Laryngopharynx
Copyright 2009, John Wiley & Sons, Inc.
Larynx
Short passageway connecting laryngopharynx with trachea Composed of 9 pieces of cartilage
Thyroid cartilage or Adam’s apple Cricoid cartilage hallmark for tracheotomy
Epiglottis closes off glottis during swallowing Glottis – pair of folds of mucous membranes, vocal folds (true vocal cords, and rima glottidis (space) Cilia in upper respiratory tract move mucous and trapped particles down toward pharynx Cilia in lower respiratory tract move them up toward pharynx
Copyright 2009, John Wiley & Sons, Inc.
Larynx
Copyright 2009, John Wiley & Sons, Inc.
Structures of Voice Production
Mucous membrane of larynx forms
Ventricular folds (false vocal cords) – superior pair
Vocal folds (true vocal cords) – inferior pair
Function in holding breath against pressure in thoracic cavity
Muscle contraction pulls elastic ligaments which stretch vocal folds out into airway Vibrate and produce sound with air Folds can move apart or together, elongate or shorten, tighter or looser
Androgens make folds thicker and longer – slower vibration and lower pitch Copyright 2009, John Wiley & Sons, Inc.
Copyright 2009, John Wiley & Sons, Inc.
Movements of Vocal Cords
Chapter 22, Respiratory System
Figure 22.5 13
Trachea
Extends from larynx to superior border of T5
4 layers
Divides into right and left primary bronchi Mucosa Submucosa Hyaline cartilage Adventitia
16-20 C-shaped rings of hyaline cartilage
Open part faces esophagus
Copyright 2009, John Wiley & Sons, Inc.
Location of Trachea
Copyright 2009, John Wiley & Sons, Inc.
Bronchi
Right and left primary bronchus goes to right lung Carina – internal ridge
Divide to form bronchial tree
Most sensitive area for triggering cough reflex Secondary lobar bronchi (one for each lobe), tertiary (segmental) bronchi, bronchioles, terminal bronchioles
Structural changes with branching
Mucous membrane changes Incomplete rings become plates and then disappear As cartilage decreases, smooth muscle increases
Sympathetic ANS – relaxation/ dilation Parasympathetic ANS – contraction/ constriction
Copyright 2009, John Wiley & Sons, Inc.
Copyright 2009, John Wiley & Sons, Inc.
Copyright 2009, John Wiley & Sons, Inc.
Lungs
Separated from each other by the heart and other structures in the mediastinum Each lung enclosed by double-layered pleural membrane
Pleural cavity is space between layers
Parietal pleura – lines wall of thoracic cavity Visceral pleura – covers lungs themselves Pleural fluid reduces friction, produces surface tension (stick together)
Cardiac notch – heart makes left lung 10% smaller than right
Copyright 2009, John Wiley & Sons, Inc.
Relationship of the Pleural Membranes to Lungs
Copyright 2009, John Wiley & Sons, Inc.
Copyright 2009, John Wiley & Sons, Inc.
Anatomy of Lungs
Lobes – each lung divides by 1 or 2 fissures
Each lobe receives it own secondary (lobar) bronchus that branch into tertiary (segmental) bronchi
Lobules wrapped in elastic connective tissue and contains a lymphatic vessel, arteriole, venule and branch from terminal bronchiole Terminal bronchioles branch into respiratory bronchioles which divide into alveolar ducts About 25 orders of branching
Copyright 2009, John Wiley & Sons, Inc.
Microscopic Anatomy of Lobule of Lungs
Copyright 2009, John Wiley & Sons, Inc.
Alveoli
Cup-shaped outpouching Alveolar sac – 2 or more alveoli sharing a common opening 2 types of alveolar epithelial cells
Type I alveolar cells – form nearly continuous lining, more numerous than type II, main site of gas exchange Type II alveolar cells (septal cells) – free surfaces contain microvilli, secrete alveolar fluid (surfactant reduces tendency to collapse)
Copyright 2009, John Wiley & Sons, Inc.
Alveolus
Respiratory membrane
Alveolar wall – type I and type II alveolar cells Epithelial basement membrane Capillary basement membrane Capillary endothelium Very thin – only 0.5 µm thick to allow rapid diffusion of gases
Lungs receive blood from
Pulmonary artery - deoxygenated blood Bronchial arteries – oxygenated blood to perfuse muscular walls of bronchi and bronchioles
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Components of Alveolus
Copyright 2009, John Wiley & Sons, Inc.