142776946-penatalaksanaan-dispepsia.doc

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PENATALAKSANAAN DISPEPSIA DIAGNOSTIK Anamnese, pemeriksaan fisik, laboratorium, Endoskopi, pemeriksaan radiologis DIAGNOSTIK WORK – UP Pud, Gerd, Gastric & Oesophageal Cancer harus disingkirkan DIAGNOSTIC OPTIONS •

Evaluasi Diagnostic – Endoscopy awal – H. Pylory Test



Terapi empiris Algoritme diagnosis dispepsia DISPEPSIA BELUM DIINVESTIGASI

EVALUASI KLINIS : ANAMNESA, PEM. FISIK PERHATIKAN ALARM SIMPTOM Pertimbangkan : Gastroesofageal reflux Faktor diet, obat2tan,sindroma kolon teriritasi, peny. Jantung, peny pankreasbilier, kelainan sistemik

penderita usia > 50 tahun, alarm symptom, keganasan atau kelainan organik

penderita usia < 50 tahun, tidak ada alarm simptom

ENDOSKOPI

KELAINAN ORGANIK

NORMAL

TERAPI

DISPEPSIA FUNGSIONAL

Noninvasif tes H pylori terapi bila (+)

MEDIKAMENTOSA

Gejala atau HP (+), terapi empiris PPI atau endoskopi

ENDOSKOPI

Recurrent atau Gejala menetap

Terapi empiris PPI

Gejala menetap Non invasif test & terapi HP atau endoskopi

A. ANTASID  Baik untuk menetralkan asam lambung B. ANTISEKRESI ASAM LAMBUNG  Antagonis H2 reseptor  Proton Pump Inhibitor  Selective Muscarinic Blocking Agent (Pirenzepine) C. SITOPROTEKTIF  Sitoprotektif : Sukralfat, Setraksat  Prostaglandin – E analog : Misoprostol, Enprostil D. OBAT PROKINETIK  Metoklopramid, Domperidone, Cisapride, Erithromisin, Loxiglumide E. PENGOBATAN H. PYLORI F. OBAT ANALGETIK VISERAL  Fedotozine, Ondansetron, Sumatriptan G. OBAT ANTIDEPRESI  Mianserin, Imipramine H. SIMETHICHONE I. LAIN – LAIN  Nitrate, Mebeverine

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