Welcome to Block 6 Basic Medical Science III HOMEOSTASIS AND METABOLISM
Learning Objectives
Metabolism • Metabolism consists of catabolism and anabolism • Catabolism: degradative pathways – Usually energy-yielding!
• Anabolism: biosynthetic pathways – energy-requiring!
Organization in Pathways • • • • •
Pathways consist of sequential steps The enzymes may be separate Or may form a multienzyme complex Or may be a membrane-bound system New research indicates that multienzyme complexes are more common than once thought
Nutrition • Protein is a rich source of nitrogen and also provides essential amino acids • Carbohydrates provide needed energy and essential components for nucleotides and nucleic acids • Lipids provide essential fatty acids that are key components of membranes and also important signal molecules
Organ Systems Interrelationships • Nutrients and oxygen are distributed by the blood • Metabolic wastes are eliminated by the urinary and respiratory systems Figure 1.2
Homeostasis • Homeostasis – System Communications (feed back, transduction, etc) – Homeostasis & Disturbance of Homeostasi – Physiological adaptation
Block 6 Homeostasis and Metabolism • Lectures : 27 times • Practical and skill lab (11 times): – Practical – Skill lab
: 9 topics : 2 topics
• Tutorial (4 times) – Homeostasis – Metabolism – Adaptation
: 1 topics : 2 topics : 1 topics
Block 6 Homeostasis and Metabolism Assessment: - Individual assignment (10%) - Written test (40%) - SOCA (30%) - OSCE and Practical (20%)
Rules of Lecture WHEN LECTURE IS GOING ON:
• • • • •
Don’t play internet. Turn off your laptop. Concentrate on the lesson. Don’t play your hand-phone. Don’t walking in and out of the classroom without permission.
COME TO CLASS AND READ THE BOOK BEFORE LECTURE
Rules in Labs • General rules: – Using lab coat and name tag – Authorized persons only can access labs – Using lab tools or materials carefully (microscope; chemical material, etc.) – Eating, drinking, smoking NOT ALLOWED – Be seriously
Contact persons: • dr. Hasrul Han, M.Phil – Clinical Pathology Department
• dr. Yanti Rosita, M.Kes – Biochemistry Department