Weaning From IABP Ri
王昭閎
IntraAortic Balloon Pump
Settings: catheter-mounted, balloon volume 30-50 ml, central lumen, helium, synchronization. Net effect: myocardial oxygen supply/demand ratio with a small increase in systemic perfusion (≦0.5L/min) Timing: Pre-,Peri-,Post-op
IABP Waveforms
IABP
Early Inflation
Waveforms
Late Inflation
IABP
Early Deflation
Waveforms
Late Deflation
Indications
Cardiogenic shock Mechanical complication of AMI In association with CABG In association with nonsurgical revascularization Stabilization of cardiac transplant recipient before insertion of ventricular assist device Postinfarction angina Ventricular arrhythmias related to ischemia
Contraindications Absolute Contraindications
Aortic valve insufficiency; Aortic dissection
Relative Contraindications
Femoral arterial insertion: Abdominal aortic aneurysm; Severe calcific aortoiliac or femoral arterial disease Percutaneous insertion: Recent ipsilateral groin incision; Morbid obesity
Complications Complication rate: 5-47% Limb ischemia; aortic dissection; aortoiliac
laceration; perforation; deep wound infection Bleeding at insertion site; superficial wound infections; asymptomatic loss of peripheral pulse; lymphocele
Weaning from IABP
Continued satisfactory LV performance Augmentation curve remains < SBP No further increase in CO at 1:1 assist rate in comparinson with 1:2
Weaning from IABP No experimental or clinical studies have
been done to evaluate the most effective weaning Traditional method: reduce the assist rate from 1:1 to 1:2, etc, because all consoles are equipped with it. The method of weaning is, at best, selected arbitrarily.
Weaning from IABP
Traditional method:↓Assist rate while maintaining augmentation. New method: ↓Augmentation while rate at 1:1 Goal: assure satisfactory cardiac performance independent of balloon pump assist. Weaning is done in a gradual fashion over a preset time interval (in two phases) Criteria for initiation of IABP weaning: a patient must be in hemodynamic class I (Shock box)
Weaning from IABP
Shock Box
Left Ventricular Stroke Work Index LVSWI = (SV/BSA)*(MAPPCWP)*(0.0136) Normal = 45-75 Class I: Minimal failure group Class II: Hypovolemic group Class III: HypervolemicHyperdynamic group Class IV: Classic cardiogenic shock (HypervolemicHypodynamic group)
Protocols
Initial set of hemodynamic data Phase I: 1:2 + 100% V.S. 75% + 1:1 Appropriate therapeutic measure Parameters:↓LVSWI or↑PWP > 20% If not class I, 1:1 + 100% for more 12-24 hr Phase II: 1:3 + 100% V.S. 50% + 1:1 Flutter mode (<25%) for 10-15 min; Prevent clot Augmentation(%) adjustment by pressure; variable balloon volume changes
Results
75% + 1:1 similar to 1:2 + 100% Class I p’t in Phase II: min. change between phases
Phase II as balloon “off” or “flutter”
Combined methods is safe and reliable IABP < 3-4 hrs, weaning may be shortened to 1-2 hrs Average time from class IV to I: 48 hrs
One Patient’s Data
Criteria for Variant Condition
Preoperatively or acute ventricular dysfunction ~1 hr devided into two 30-minute phases
Criteria for Variant Condition
Emergency basis (at the completion of a cardiac operation), IABP should not be DC early after satisfactory response Maybe 12-18 hours later in ICU
Criteria for Variant Condition
Weaning in Special Situations Prolonged Respiratory Support
Never weaning simultaneously DC respiratory support first, if possible 12-24 hr later, weaning may be attempted COPD or ARDS, IABP may be weaned first
Pressor Therapy
Vasopressor to the lowest level before weaning Exception: Leg ischemia. Early removal or change site Change all the pressor drugs to dopamine or dobutamine Decrease to <5mcg/kg/min, then weaning Within 12-24 hr after DC IABP, decrease in conc. and DC DC pressor but keep IABP as bridge to trans.
Thanks for Your Attention
References
Clinical Application of Intra-Aortic Balloon Pump, Third Edition. Hooshang Bolooki. Counterpulsation: historical background, technical improvements, hemodynamic and metabolic effects," which appears in Volume 84 (1994) of the journal Cardiology (pp. 156-167). Braunwald: Heart Disease: A Textbook of Cardiovascular Medicine, 6th ed.