Cutaneous & Subcutaneous Mycosis
Dr. Mejbah uddin Ahmed
Classification Medical Mycoses are classified according to the tissue levels initially colonized: Superficial mycoses Cutaneous mycoses Subcutaneous mycoses Systemic mycoses due to primary pathogens Systemic mycoses due to opportunistic pathogens
Superficial mycoses
Limited to the outermost layers of the skin and hair.
Tinea versicolor: The causative agent is Malassezia furfur.
Clinical feature: Commonly affect the skin of the chest, back, upper arms and legs. The lesions are either lighter than the skin or a reddish-brown. It doesn't usually affect the face.
Cutaneous mycoses
Localized to the epidermis, hair & nails
Restricted to keratinized tissue
The organisms that cause cutaneous diseases are called dermatophytes and the diseases are called ringworm or tinea.
Dermatophytoses
Dermatophytoses ( tinea, ringworm) are chronic infection and are caused by fungi of three genus: Epidermophyton: Skin + nail Trichophyton: Skin + hair + nail Microsporum : Hair + nail
Fungal Infection Nomenclature
Tinea capitis- scalp.
Tinea pedis- feet.
Tinea unguium- nails.
Tinea corporis- body.
Tinea cruris- groin, or jock itch.
Transmission: Direct contact with skin scales.
Epidermophyton spp.
Microsporum spp.
Most dermatological fungal infections arise from one of three genera of fungi. Trichophyton spp.
Tinea pedis
The most common fungal infection amongst humans.
Tinea capitis
Tinea unguium (Also known as onychomycosis )
Tinea corporis
Occurs all over the body.
Tinea cruris
Subcutaneous Mycoses
These are caused by fungi that grow in the soil & on vegetation and are introduced into subcutaneous tissue through trauma.
Sporothrix schenckii: Causes local pastule or ulcer with nodules along with the draining lymphatics.
Mycetoma
Mycetoma: Is a chronic subcutaneous infection caused by saprophytic species of fungus or actinomycetus bacteria that normally found on the soil.
Organisms: Pseudallescheria boydii, Madurella mycetomatis, Madurella grisa etc.
Transmission: Traumatic inoculation.
Mycetoma
Clinical features:
Pathology is characterized by suppuration, abscess formation, granuloma and formation of draining sinus.
The process may spread to contagious muscle and bone.
Untreated cases may persist several years causing deformation and loss of function.
Mycetoma Lab. Diagnosis: Study of granules: Pigmented hyphae. Culture.