Sto Lympathic System.docx

Lymphatic System and Immunity Objectives 1. Describe the functions of the lymphatic system. 2. Explain how lymph is formed. 3. Describe how lymph is transported. 4. Describe the structure and function of tonsils, lymph nodes, the spleen, and the thymus. 5. Define the concepts of specificity and memory as they apply to immunity. 6. Define innate immunity, and describe the cells and chemical mediators involved. 7. List the events of an inflammatory response, and explain their significance. 8. Define antigen. 9. Describe the origin, development, activation, and proliferation of lymphocytes. 10. Define antibody-mediated immunity and cell-mediated immunity, and name the cells responsible for each. 11. Diagram the structure of an antibody, and describe the effects produced by antibodies. 12. Discuss the primary and secondary responses to an antigen. Explain the basis for long-lasting immunity. 13. Describe the functions of T cells. 14. Explain the four ways that adaptive immunity can be acquired. 15. Explain how innate, antibodymediated, and cell-mediated immunity can function together to eliminate an antigen. 16. Describe how aging affects

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Topic Content Functions of Lymphatic System 1. Fluid Balance 2. Lipid Absorption 3. Defense against foreign substances and pathogens Anatomy of Lymphatic System Structure and Functions 1. Lymph 2. Lymphocytes 3. Lymphatic vessels 3.1 Lymphatic trunk  Jugular trunk  Subclavian trunk  Bronchomediastinal  Intestinal trunk  Lumbar trunk 3.2 Right Lymphatic duct 3.3 Thoracic duct 3.4 Flow of the Lymph  Blood capillaries (blood)  interstitial spaces (interstitial fluid)  lymphatic capillaries (lymph)  lymphatic vessels (lymph)  lymphatic trunk (lymph)  lymphatic duct (lymph)  junction of internal jugular and subclavian veins (blood) 4. Lymph nodes 4.1 Lymphatic nodules 5. Tonsils 6. Spleen 7. Thymus Overview of Lymphatic System 1. B cells 2. T cells Immunity  Specificity  Memory Innate Immunity 1. Physical Barrier 2. Chemical Barriers 3. White Blood Cells 4. Inflammatory Response 4.1 Local Inflammation 4.2 Systemic Inflammation

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Adaptive Immunity 1. Antibody-mediated immunity 1.1 Antibodies  IgG  IgA  IgM  IgE  IgD 1.2 Self-Antigens 2. Cell mediated immunity 2.1 Memory T cells Acquired Immunity 1. Active Natural Immunity 2. Active Artificial immunity 3. Passive Natural Immunity 4. Passive Artificial immunity Effects of Aging on the Lymphatic System and Immunity

References: Tate, P. (2011). Principles of Anatomy and Physiology 2nd Edition. McGraw-Hill Education, NY. Tortora, G., (2016). Principles of Anatomy & Physiology 1st Asia-Pacific Edition. John Wiley & Sons, Ltd. VanPutte, C., Regan, J., Russo, A. (2016). Seeley’s Essentials of Anatomy & Physiology 9th Edition, Chapter 1-3. McGraw-Hill Education, NY.