Situational Analysis On Neoplasia

University of Santo Tomas DEPARTMENT OF PATHOLOGY

SITUATIONAL ANALYSIS ON NEOPLASIA DR. MENNEN A. ALSOL

CASE 1 • A 45 year old former guest relation officer complained of on and off vaginal bloody discharge for the past 3 years. She had previous pap smear and the latest was known to be abnormal.

DISCUSS: Which of the 3 pap smear slides is compatible with the patient’s history?

B

A C

• Colposcopy with cervical biopsy was done. The cervix showed:

Cervical biopsy showed:

LPO

HPO

Case 1 1. Give the Diagnosis 2. What is the etiopathogenesis? 3. Discuss tumor grading and staging in reference to the case.

CASE 2 4 years ago, a 60 year old bank manager had his annual executive check-up. Colonoscopy and biopsy showed:

1. Give the diagnosis and discuss preneoplastic consideration.

• One month ago patient complained of changes in bowel habits, with occasional rectal bleeding and weight loss. Carcinoembryonic antigen (CEA) was elevated. Patient was subjected to surgery colectomy showed:

• Cont..

1. Give the diagnosis. 2. Describe the phenotypic features of this tumor. 3. Describe the grading and staging of the tumor .

CASE 3 •

A 22 year old medical student consulted because of breast mass noted 2 years ago. The mass is movable and slightly painful. Excision biopsy showed:

Cont..

1. Give the nomenclature of the mass. 2. Discuss the prognosis of the patient

CASE 4 •

A 13 year old high school student complained of abdominal enlargement. A pelvic mass was noted on ultrasound. Oophorectomy was done and showed:

Cont..

Cont.. 1. 2. 3. 4.

Give the nomenclature of the tumor. Discuss the gross and the histologic features. What is the role of tumor markers in this case? Give the prognosis of the patient.