Central Nervous System Michelle Y. So, M.D.
Case 1 A 52 – year old hypertensive male complained of headache and became unconscious. He was admitted and eventually expired after one month . Autopsy was done with the following findings.
Case 1
Case 1 1. Given the previous autopsy findings, give your diagnosis . 2. Give the gross and microscopic findings. 3. Give the etiology .
Case 1 4. Also discuss the etiology of subarachnoid hemorrhage and combined intracerebral & subarachnoid bleed.
Case 2 A 5 – year old boy complained of headache with high grade fever. When he was admitted, he was noted to already have decreased sensorium. Physical examination showed the presence of nuchal rigidity. Patient expired after two weeks.
Case 2
Case 2 1. Given the previous autopsy findings , what is your diagnosis. 2. Give the gross and microscopic findings. 3. If CSF examination were done, what are the expected findings.
Case 2 4. Given the age of the patient , what is the most likely etiologic agent ? Give the most likely etiologic agents for newborns, adolescents and young adults , for the elderly age group.
Case 3 • A 60 year old male complained of headache and right-sided body weakness. He has been previously diagnosed with bronchogenic carcinoma. He was admitted to the hospital and eventually expired after one month. Autopsy was performed.
Case 3 - A
Case 3 - A
Case 3 - B
Case 3 - B
Case 3 1. Given the clinical history , which of the two cases is the more likely diagnosis ? 2. What is the diagnosis of the other case. 3. Classify the two tumors whether primary or secondary.
Case 3 4. Give the gross and microscopic findings for both cases. 5. What are the most common primary sites of metastatic tumors to the CNS ?