Seroquel Pine

NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms) Generic Name Quetiapine Peak Unknown

Trade Name Seroquel

Classification Antipsychotics

Onset Unknown

Dose 100 mg

Duration 8-12 hours

Route PO

Time/frequency HS

Normal dosage range 100-800 mg

Why is your patient getting this medication Stabilize mood

For IV meds, compatibility with IV drips and/or solutions N/A

Mechanism of action and indications (Why med ordered) Probably acts by serving as an antagonist of dopamine and serotonin. Also antagonizes histamine H1 receptors and alpha1-adrenergic receptors. Indicated for Schizophrenia and Bipolar mania

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity, Use cautiously in history of suicide attempts, hepatic impairment. Common side effects Dizziness and weight gain

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Alcohol, opioid analgesics, and sedative/hyponotics,

Lab value alterations caused by medicine May cause asymptomatic increase in AST andALT

Phenytoin ↑ clearance and ↓ effectiveness of quetiapine (dose change may be necessary)

Nursing Process- Assessment (Pre-administration assessment) Monitor mental status, blood pressure, Monitor mood changes. Assess for suicidal tendencies, especially during early therapy. Restrict amount of drug available to patient. Observe patient carefully when administering to ensure medication is swallowed and not hoarded

Be sure to teach the patient the following about this medication Take medication as directed. Inform of possibility of extrapyramidal symptoms. Advise to change position slowly to minimize orthostatic hypotension. May cause drowsiness. Avoid extremes in temp. Notify health care provider promptly of sore throat, fever, unusual bleeding bruising or rash. Emphasize need for follow up. Opthalmologic exams should be preformed before and every 6 months during therapy, Caution patient to avoid concurrent use of alcohol, other CNS depressants

Assessment Why would you hold or not give this med? If extrapyramidal side effects are present a reduction or discontinuation may be necessary, Monitor for tardive dyskinesia (involuntary rhythmic movement of mouth, face, and extremities). Report immediately; may be irreversible.

Evaluation Check after giving Decreased in excited, manic, paranoic, or withdrawn behavior