Pharmacology1(medical Pharmacology)

Medical Pharmacology

DURGE RAJ GHALAN Department of Pharmacology, Sun Yat-sen University School of Medicine

Chapter I Introduction  Definitions  1)

Pharmacology



Pharmacodynamics



Pharmacokinetics

 2)

Drugs

What is Pharmacology? Pharmacology can be defined as the study of substances (drugs) that interact with living systems (body) through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes.

Drug-Body Interactions The interactions between a drug and the body are conveniently divided into two classes.

Pharmacodynamics:

the actions of the drug on

the body are termed pharmacodynamic processes.

Pharmacokinetics:

the actions of the body on the

drug are called pharmacokinetic processes.

What are drugs? A drug may be defined as any chemical substance that brings about a change in biologic function through its chemical actions, is used to prevent, diagnose, and treat diseases.

What are poisons? Poisons are chemicals that do harm to the body in small dose. For example: Toxins like pertussis toxin, cholera toxin are poisons of biologic origin, in contrast to inorganic poisons such as lead and arsenic.

What is the relationship between drugs and poisons? Similarity: they are all chemicals. Difference: dosage Drugs

poisons

What is food? Food

provides life essential to the body, such as carbohydrates, proteins, lipids, vitamins, and trace elements.

FDA:

Food and Drug Administration

Reference books: 1. Basic & Clinical Pharmacology, 10th edition, edited by Professor Bertram G. Katzung, MD, PhD and published by Lange Medical Books 2. Goodman & Gilman’s the Pharmacological Basis of Therapeutics, 10th edition (McGraw-Hill,2001)