Pchem > F2002 Quiz 8

  • November 2019
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V

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Name: h f,Y PHR 142P- Quiz#8 - F2002

(points)

(2) 1 Ephedrineis a weakly basicdrug with Ku : 2.3 x IIa . Define intrinsic partition coefficient for ephedrine.

,

fFl

V =::3 f\! [E]

[u: i, 6fc \o

(2) 2. Define apparentpartition coefficientfor a weak acid.

K*

:

lrrn]" t-.^-1

r

'1

LA-J* LHAJ,,n

(2) 3. Write an equationwhich relatesKuooto pH for a weak acid. Be certain

(4) 4.Sketch a graphof Kuoovs pH for a weakacid. Indicatepredominantspecies at variouspoints on the graphand indicatesignificant featuresjust as has beendone in lecture.

Ko u,.{

H.K K,7,

1l \

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