Molecular Genetics

MOLECULAR GENETICS

Chromosome s

contains

Nucleus

made up of

DNA

which comprises

Genes comprises

has carries

Basic unit

Genetic Engineering Genetic Code

called

produces

to control composed of

Deoxyribose sugar forms

Phosphate group

Base

Synthesis of specific polypeptide s

Sugar phosphate backbone Makes up the

Adenine (A) Thymine (T) Cytosine (C) Guanine (G)

which determines

Specific structure & function of protein

DNA strand

In the shape of

Double helix

Gene cloning

Ethical & social issues in

Has the

Gene therapy GM foods Pharmaceuticals

requires

(i) to cut

Restriction Enzyme Vector

Complementary base pairing A-T C-G

(ii) which are joined by (iii) inserted into

(iv) to produce

Gene of Interest

+

e.g. E.coli plasmid pair up with one another

Links two

Transgenic organism

Basic Steps

includes 4 types

Also has

Used in

Nucleotide

e.g. human insulin gene

Ligase Host Bacterium Gene Product

e.g. insulin