Met A Hemoglobin A

  • November 2019
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CAUSAS: DROGAS:

DAPS, FENAZOPIRIDINA, ANESTESICOS LOCALES, VASODILATADORES CORONARIOS SUST. QUIM.: ANILINAS, NITRITOS y NITRATOS (Agua de pozo, Aditivos), NITROBENCENO

MECANISMO DE ACCION •OXIHEMOGLOBINA (FERROSO)

METAHEMOGLOBINA (FERRICO)

INCAPACIDAD DE TRANSPORTE OXIGENO

•DESPLAZAMIENTO A LA IZQUIERDA DE LA CURVA DE DISOCIACION DE Hb METAHb

SINTOMAS

10 - 15 %

CIANOSIS PERIFERICA

20 - 30 %

CIANOSIS GENERALIZADA, CEFALEA, TAQUICARDIA

30 - 40 %

DISNEA, TAQUICARDIA, VERTIGO, CEFALEA

40 - 50 %

DEPRESION S.N.C., TAQUIPNEA, TAQUICARDIA, HIPOTENSION

60 - 70 %

COMA, CONVULSIONES, ARRITMIAS CARDIACAS, SHOCK

MAS 70 %

MUERTE

LABORATORIO: METAHEMOGLOBINA (NORMAL 1 - 3 %) SANGRE ACHOCOLATADA TRATAMIENTO: DECONTAMINACION OXIHEMOGLOBINA

METAHEMOGLOBINA

METAHb Reductasa AZUL DE METILENO

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