Measures Of Frequency-1
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MEASURES OF DISEASE FREQUENCY A Presentation
EPIDEMIOLOGY is the study of frequency, distributions and determinants of health related states and events in human populations, and the application of this study to control health problems.
Frequency is the measurement of disease, disability, or death and converting this information into rates or ratios. [ Incidence, Prevalance and Death rates. This yields magnitude of the problem.
To investigate distributions and determinants of disease, it is necessary to know: The
size of the source population from which
affected individuals were derived The
time period during which the data were
collected.
RATIO
The most basic measure
Obtained by simply dividing one quantity by another without implying any specific relationship between the numerator and denominator, such as the number of stillbirths per thousand live births.
In ratio, the numerator & denominator are mutually exclusive.
PROPORTION A
proportion is a type of ratio in which those who are included in the numerator must also be included in the denominator.
For
example: the proportion of women over the age of 50 who have had a hysterectomy, or the number of fetal deaths out of the total number of births (live births plus fetal deaths).
RATE A
rate is a proportion with specifications of time. It is a ratio in which there is a distinct relationship between the numerator and denominator with a measure of time being an intrinsic part of the denominator.
For
example, the number of newly diagnosed cases of breast cancer per 100,000 women during a given year.
IMPORTANT POINT
It is necessary to be very specific about what constitutes both the numerator and the denominator. In some circumstances, it is important to make clear whether the measure represents the number of events or the number of individuals.
For example, the frequency of myopia among a population of school children could represent the number of affected eyes in relation to total eyes, or the number of children affected in one or both eyes relative to all students.
PREVALENCE
Prevalence quantifies the proportion of individuals in a population who have the disease at a specific instant and provides an estimate of the probability (risk) that an individual will be ill at a point in time
It is a measure of current status of the disease.
PREVALENCE
The formula for calculating the prevalence P = number of existing cases of a disease divided by total population (at a given point in time)
POINT PREVALENCE Prevalence
can be thought of as the status of the disease in a population at a point in time and as such is also referred to as point prevalence. This "point" can refer to a specific point in calendar time or to a fixed point in the course of events that varies in real time from person to person, such as the onset of menopause or puberty or the third postoperative day.
PERIOD PREVALENCE It
represents the proportion of cases that exist within a population at any point during a specified period of time. The numerator thus includes cases that were present at the start of the period plus new cases that developed during this time
INCIDENCE: Incidence
quantifies the number of new events or cases of disease that develop in a population of individuals at risk during a specified time interval.
INCIDENCE: The
number of new events or cases of a specific disease during a given time divided by Population at risk [during a specified time interval.]
Cumulative incidence (CI) is
the proportion of people who become diseased during a specified period of time. It provides an estimate of the probability, or risk, that an individual will develop a disease during a specified period of' time
Mid Interval Population Means
the population in the middle of that specified period e.g. for a whole year, 1st July is mid interval.
Issues in the Calculation of Measures of Incidence For
any measure of disease frequency, precise definition of the denominator is essential for both accuracy and clarity. This is a particular concern in the calculation of incidence. The denominator of a measure of incidence should include only those who are considered "at risk" of developing the disease.
Contd. That
is, the total population from which the new cases could arise. Consequently, those who currently have or have already had the disease under study or persons who cannot develop the disease for reasons such as age, immunization, or prior removal of the involved organ should be excluded from the denominator.
MORBIDITY RATE is the number of nonfatal cases in the total population at risk during a specified period of time.
For
example, the morbidity rate of tuberculosis (TB) in the U.S.
in 1982 can be calculated by dividing the number of nonfatal cases newly reported during that year by the total U.S. midyear population Morbidity rate of TB = 25,5201231,534,000/year = 11.01101/Year Thus,
in 1982, the morbidity rate or incidence rate of nonfatal TB in the United States was 1 1.0 per 100,000 population.
MORTALITY RATE It
expresses the number of deaths in a particular population during a period of time. It is calculated the number of fatalities divided by the total population. during that period.
Proportionate Mortality Rate It
measures the proportions of deaths from a specified cause relative to all deaths in a particular population during a period of time. It is calculated the number of fatalities due to a specified disease divided by the total number of deaths reported during that period.
Case Fatality Rate It
measures the number of deaths from a specified disease divided by the total number of case of that disease reported during that period.
EPIDEMIOLOGY is the study of frequency, distributions and determinants of health related states and events in human populations, and the application of this study to control health problems.
Frequency is the measurement of disease, disability, or death and converting this information into rates or ratios. [ Incidence, Prevalance and Death rates. This yields magnitude of the problem.
To investigate distributions and determinants of disease, it is necessary to know: The
size of the source population from which
affected individuals were derived The
time period during which the data were
collected.
RATIO
The most basic measure
Obtained by simply dividing one quantity by another without implying any specific relationship between the numerator and denominator, such as the number of stillbirths per thousand live births.
In ratio, the numerator & denominator are mutually exclusive.
PROPORTION A
proportion is a type of ratio in which those who are included in the numerator must also be included in the denominator.
For
example: the proportion of women over the age of 50 who have had a hysterectomy, or the number of fetal deaths out of the total number of births (live births plus fetal deaths).
RATE A
rate is a proportion with specifications of time. It is a ratio in which there is a distinct relationship between the numerator and denominator with a measure of time being an intrinsic part of the denominator.
For
example, the number of newly diagnosed cases of breast cancer per 100,000 women during a given year.
IMPORTANT POINT
It is necessary to be very specific about what constitutes both the numerator and the denominator. In some circumstances, it is important to make clear whether the measure represents the number of events or the number of individuals.
For example, the frequency of myopia among a population of school children could represent the number of affected eyes in relation to total eyes, or the number of children affected in one or both eyes relative to all students.
PREVALENCE
Prevalence quantifies the proportion of individuals in a population who have the disease at a specific instant and provides an estimate of the probability (risk) that an individual will be ill at a point in time
It is a measure of current status of the disease.
PREVALENCE
The formula for calculating the prevalence P = number of existing cases of a disease divided by total population (at a given point in time)
POINT PREVALENCE Prevalence
can be thought of as the status of the disease in a population at a point in time and as such is also referred to as point prevalence. This "point" can refer to a specific point in calendar time or to a fixed point in the course of events that varies in real time from person to person, such as the onset of menopause or puberty or the third postoperative day.
PERIOD PREVALENCE It
represents the proportion of cases that exist within a population at any point during a specified period of time. The numerator thus includes cases that were present at the start of the period plus new cases that developed during this time
INCIDENCE: Incidence
quantifies the number of new events or cases of disease that develop in a population of individuals at risk during a specified time interval.
INCIDENCE: The
number of new events or cases of a specific disease during a given time divided by Population at risk [during a specified time interval.]
Cumulative incidence (CI) is
the proportion of people who become diseased during a specified period of time. It provides an estimate of the probability, or risk, that an individual will develop a disease during a specified period of' time
Mid Interval Population Means
the population in the middle of that specified period e.g. for a whole year, 1st July is mid interval.
Issues in the Calculation of Measures of Incidence For
any measure of disease frequency, precise definition of the denominator is essential for both accuracy and clarity. This is a particular concern in the calculation of incidence. The denominator of a measure of incidence should include only those who are considered "at risk" of developing the disease.
Contd. That
is, the total population from which the new cases could arise. Consequently, those who currently have or have already had the disease under study or persons who cannot develop the disease for reasons such as age, immunization, or prior removal of the involved organ should be excluded from the denominator.
MORBIDITY RATE is the number of nonfatal cases in the total population at risk during a specified period of time.
For
example, the morbidity rate of tuberculosis (TB) in the U.S.
in 1982 can be calculated by dividing the number of nonfatal cases newly reported during that year by the total U.S. midyear population Morbidity rate of TB = 25,5201231,534,000/year = 11.01101/Year Thus,
in 1982, the morbidity rate or incidence rate of nonfatal TB in the United States was 1 1.0 per 100,000 population.
MORTALITY RATE It
expresses the number of deaths in a particular population during a period of time. It is calculated the number of fatalities divided by the total population. during that period.
Proportionate Mortality Rate It
measures the proportions of deaths from a specified cause relative to all deaths in a particular population during a period of time. It is calculated the number of fatalities due to a specified disease divided by the total number of deaths reported during that period.
Case Fatality Rate It
measures the number of deaths from a specified disease divided by the total number of case of that disease reported during that period.
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