Mcguirewoods Presentation V2

Æsis Research Group Ogan Gurel, MD MPHIL Chairman

McGuireWoods Presentation - 4 October 2006 Private Equity Investment in Health Care: Key Trends & Opportunities I would like to emphasize some aspects of the field of convergent medical technologies (CMT) which was the focus of Duravest and continues to be a specialty area of mine. In addition, I’d like to emphasize some important themes currently (and in the future of healthcare/life sciences investing) which will be important for all parties to keep in mind. Themes 1. 2.

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Acceleration of medical technology critical Importance of partnerships a. The demand by baby boomers for convenience b. The rise of convergent and combination medical technologies c. The growing importance of safety Decreasing importance of intellectual property per se a. Technology develops so rapidly that patent protection can in fact be obsolete even before it expires. b. Medical technology increasingly is based on combinations of individual technologies. Safety of critical importance a. Greater Efficacy of Medicine b. The Coming of Age of the Baby Boomers c. The Rise of Chronic Diseases d. Aggressive Prevention Influence of government increasing

Convergent medical technologies 1.

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The future of medicine a. Personalized medicine b. Precision medicine c. Merging of disciplines d. Drivers of growth in CMT i. Advances in minimally invasive surgery (MIS) ii. Miniaturization of electronics iii. Closing the loop between diagnostics, therapeutics and personalized medicine iv. Demand for convenience v. Growing importance of safety Builds in safety considerations Leverages partnerships Rapid development of market-ready products a. By combining “off-the-shelf” components

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