Main Project Topics

PROJECTS TOPICS A) Database Development:

*Integration of databases and software packages for addressing complex issues in Biotechnology. *Development of Value added, dedicated and derived databases such as SNP, EST etc. on various genomes.

*Regulation of the vitamin metabolism and transport in bacteria by a conserved RNA structural element. *Inferring combinatorial regulation of transcription in silico. *Comparative analysis of orthologous eukaryotic mRNAs: potential hidden functional signals. *Deciphering the cis-regulatory logic of coregulated genes.

*Documentation of biodiversity resources for appropriate utilization. *Development of clinical information databases of different diseases. *Development of Immunoinformatics based databases. *Development of databases based on regulatory genomics.

*Identification of over-represented transcription factor binding sites in co-expressed genes. *A multiple-feature framework for modeling and predicting transcription factor binding sites C) Software Development

*Development of databases related to plants genomic & analysis data.

*Development of new software tools for genomic, proteomics, immunoinformatics, transcriptomics, sequence alignment, gene prediction & related applications.

*Development of databases related to microbial genomic & analysis data.

*Development of tools for analysis of cellular functions and metabolic pathways.

*Development of databases related to Drug Designing

*Development of teaching & e-learning modules in Bioinformatics. D) In-silico Drug Discovery

B) Research Analysis *Analysis of system biology through Bioinformatics tools.

*Projects related to modeling, simulation and drug design using Bioinformatics tools and databases.

*Comparative Genomics of Prokaryotes and Eukaryotes.

*Pharmacogenomics and Bioinformatics relevant to Indian scenario.

*Detection of Conserved Regulatory Networks across Bacteria and viruses.

*Effort for virtual experimental screening of chemical libraries with important targets from major infectious diseases.

*Understanding protein structure and disease through Bioinformatics. *Regulation of genomic expression analysis pathways. *Metabolite-binding RNA domains in the genes of eukaryotes. *Identification of key pathways that support the survival of the infectious agents involved in their pathogenesis.

Specialized Topics: *Gene and Protein sequence analysis *Molecular markers *Gene annotations *Chromosomal analysis *Computational drug designing *Gene Predictions and Gene expression *Genome Analysis For more details contact

*Genetic disease profiling *Evolutionary studies/Comparative Genomics *Protein Modeling *Biological databases *Bio computing and Algorithms *Viro Informatics *Immuno informatics *Micro Array data analysis *Molecular Modeling *CADD (Computer Aided Drug Discovery) *QSAR studies Softwares Present: Commercial & Non Commercial Softwares Present Both Windows and Linux Version’s Other Academic Services Course Delivery: We under take courses delivery responsibilities on subject based, semester/ curriculum dependent from life science undergraduates and postgraduate colleges and universities. Infrastructure development: laboratory reagents, Software, and other scientific infrastructure procurements for the colleges and universities offering Life Science & Bioinformatics Courses. Content Development: Academic content development and elearning packages for Life science courses.(Teach plans, Teaching Modules, curriculum preparation, auto visuals kits, teaching aids etc.), Career Guidance: Facilitating the Campus interviews and industry visits.(Higher education admissions in India and abroad). Industry-Academic relations: We help bridging the academic andindustry relations for mutual beneficiary of men power and owledge exchange programs.( Industry visits, campus placements, Industry driven guest lectures and seminars), More Information Contact Direct to the Institute Prashantha.C.N, Managing Director Center for Bioinformatics Research Institute Chennai-600026 9176673779, or +91-44-4204 6770