Lisinopril

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NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms) Generic Name Trade Name Lisinopril Prinivil, Zestril Peak Onset 6 hr 1 hr

Classification Dose Antihypertensives 40 mg Duration 24 hr

Route PO

Time/frequency Q AM

Normal dosage range 10 mg once daily, may be increased as required range 20-40 mg once daily, maximum 80 mg/day.

Why is your patient getting this medication Treatment of hypertension

For IV meds, compatibility with IV drips and/or solutions N/A

Mechanism of action and indications (Why med ordered) ACE inhibitors block the conversion of angiotensin I to the vasoconstrictor angiotensin II. ACE also inactivates the vasodilator bradykinin and other vasodilatory prostaglandins. ACE inhibitors also increase plasma rennin levels and reduce aldosterone levels. Net result is systemic vasodilation. Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Excessive hypotension may occur with concurrent use of diuretics, other antihypertensives. Hyperkalemia may result from concurrent use of potassium supplements.

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity. Use cautiously in Geriatric patients.

Nursing Process- Assessment (Pre-administration assessment) Monitor BP & Pulse.

Common side effects Dizziness, fatigue, headache, insomnia, weakness, cough, hypotension, taste disturbances, proteinuria, fever.

Lab value alterations caused by medicine Serum K may be increased and BUN and creatinine transiently increase. NA may be decreased. CBC, may see a slight decreases in hemoglobin and hematocrit but it is rare. May cause increase in AST, ALT, alkaline phosphatase, serum bilirubin, uric acid, and glucose. Be sure to teach the patient the following about this medication Take meds as directed at the same time each day even if feeling well. Do not discontinue ACE inhibitor therapy unless directed by health care professional. Avoid salt substitutes or foods containing high levels of K or NA. Change positions slowly may cause dizziness. Assessment Evaluation Why would you hold or not give this med? Pulse <60 BP <100 systolic

Check after giving Decrease in BP Decrease in signs and symptoms.

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